Evidence map›Paper›PMID 40948672›Full record

ArticleWorld journal of diabetes2025

Autologous platelet rich gel in treatment of lower limb atherosclerotic occlusive disease in diabetic patients.

Miao Chen, Jing-Tang Li, Jia-Bao Gao, Ling Zhang, Qi-Hang Gao, Xiong Zeng, Qiang Liu

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Article in World journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miao ChenDepartment of Vascular Surgery, Jiangxi Provincial People's Hospital, Nanchang 330008, Jiangxi Province, China.
Jing-Tang LiDepartment of Vascular Surgery, Jiangxi Provincial People's Hospital, Nanchang 330008, Jiangxi Province, China.
Jia-Bao GaoDepartment of Vascular Surgery, Jiangxi Provincial People's Hospital, Nanchang 330008, Jiangxi Province, China.
Ling ZhangDepartment of Vascular Surgery, Jiangxi Provincial People's Hospital, Nanchang 330008, Jiangxi Province, China.
Qi-Hang GaoDepartment of Vascular Surgery, Jiangxi Provincial People's Hospital, Nanchang 330008, Jiangxi Province, China.
Xiong ZengDepartment of Vascular Surgery, Jiangxi Provincial People's Hospital, Nanchang 330008, Jiangxi Province, China.
Qiang LiuMedical College, Nanchang University, Nanchang 330008, Jiangxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLower limb atherosclerotic occlusive disease (LAOD) is a common complication in diabetic patients, leading to significant symptoms and reduced quality of life.

aimTo investigate the efficacy of autologous platelet-rich gel (APRG) as an innovative treatment for LAOD, focusing on clinical outcomes such as symptom relief, flow values, ankle-brachial index (ABI), walking distance, and claudication severity.

methodsThis retrospective study involved an analysis of electronic medical records (EMR) from 150 patients diagnosed with LAOD. Participants were assigned to either a treatment group (

resultsThe APRG group showed significant improvements after 12 weeks, including a 70% reduction in pain, a 65% increase in wound healing rates, and an average walking distance increase of 150 meters. Flow values improved by 20%, with significant enhancements in ABI measurements (

conclusionThe APRG demonstrates significant efficacy in managing LAOD in diabetic patients, improving key clinical parameters including flow values, ABI, walking distance, and claudication. These findings support the need for further prospective studies to validate long-term efficacy and optimize treatment strategies.

Indexed as

Ankle brachial indexAutologous platelet rich gelDiabetic patientsLower limb atherosclerotic occlusive diseaseRetrospective study

Identifiers

PMID40948672
PMCPMC12432545

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.