Evidence map›Paper›PMID 40949009›Full record

ArticleJournal of scleroderma and related disorders2025

Characteristics of patients with systemic sclerosis with aspiration: A single-center study.

Tatsuaki Naganawa, Takako Hashimoto, Naomi Ikeda, Haruna Takase, Naoki Dosoden, Kodai Ito, Marika Sawada, Yumi Ito, Natsuko Watanabe, Ai Umeda and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of scleroderma and related disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Tatsuaki NaganawaDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.ORCID https://orcid.org/0009-0003-5106-4434
Takako HashimotoDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Naomi IkedaDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Haruna TakaseDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Naoki DosodenDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Kodai ItoDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Marika SawadaDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Yumi ItoDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Natsuko WatanabeDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Ai UmedaDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Konomi AkamatsuDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Megumi KurumizawaDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Jo NishinoDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Shusaku FukayaDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Yoko InamotoFaculty of Rehabilitation, School of Health Science, Fujita Health University, Aichi, Japan.
Seiko ShibataDepartment of Rehabilitation Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Yohei OtakaDepartment of Rehabilitation Medicine, School of Medicine, Fujita Health University, Aichi, Japan.
Hidekata YasuokaDivision of Rheumatology, Department of Internal Medicine, School of Medicine, Fujita Health University, Aichi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To investigate the prevalence of aspiration and its association with GI involvement and clinical features in systemic sclerosis (SSc). Methods: Fifty patients with SSc who underwent the videofluoroscopic (VF) swallowing study were included. Aspiration was identified by the presence of aspiration and/or penetration defined by the Penetration-Aspiration Scale. The radiological findings including the residue in the oral cavity, pharynx and esophagus, which reflect oral, pharyngeal, and esophageal involvement, were also evaluated. Results: Twenty-three patients (46%) had aspiration and/or penetration. Patients with aspiration and/or laryngeal penetration had more pharyngeal vallecular residue (None 22%, Trace 44%, Mild 56%; Conclusion: In our study, about half of the patients had aspiration and/or penetration in SSc. Aspiration was associated with the extent of radiographic abnormalities of pharyngeal and esophageal involvement on the VF swallowing study. Patients with lower GI have aspiration and high UCLA GIT-2.0 scores suggesting that these patients had more severe GI manifestation.

Indexed as

aspirationlaryngeal penetrationprevalenceSystemic sclerosisvideofluoroscopic swallowing study

Identifiers

PMID40949009
PMCPMC12425942

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.