Evidence map›Paper›PMID 40949154›Full record

ReviewFrontiers in pharmacology2025

The acute adverse health effects of kratom: an evaluation of case reports.

Sarah Smallets, Sydney Litvin, Grayson Abele, Sarah Kirsh, Dennis Paustenbach

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Indole Alkaloids as Biased Opioid Receptor Modulators.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  6. 7-OH and kratom vaping products: an emerging public health threat.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah SmalletsTRC Companies, Inc., Denver, CO, United States.
Sydney LitvinTRC Companies, Inc., Denver, CO, United States.
Grayson AbeleTRC Companies, Inc., Denver, CO, United States.
Sarah KirshTRC Companies, Inc., Denver, CO, United States.
Dennis PaustenbachTRC Companies, Inc., Jackson, WY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adverse effect (AE)case reportkratom (mitragyna speciosa korth)mitragyninepolypharmacyreview

Identifiers

PMID40949154
PMCPMC12425911

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.