ArticleACS omega2025
Selenomethionine Inhibited RSV Infection-Induced Apoptosis and Inflammatory Response through ROS-Mediated Signaling Pathway.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Mitochondrial quality control: a new mechanism for antiviral therapy.Frontiers in immunology · 2026Review
- Selenium alleviates Staphylococcus aureus-induced mastitis by modulating mitochondrial dynamics and inhibiting the ROS/NLRP3/Pyroptosis pathway.Molecular biology reports · 2025Article
- Multimodal cell death drives the immunopathogenesis of RSV infection.Frontiers in immunology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory syncytial virus (RSV) is the leading pathogen of acute lower respiratory tract infections in children under 5 years of age worldwide. Respiratory syncytial virus pneumonia in infants and children causes more deaths than influenza each year due to the high rate of severe illness. There is a lack of safe and effective antiviral drugs, and the development of novel antirespiratory syncytial virus drugs is of great clinical importance. Selenomethionine (SeMet), as the main ingredient in commercially available selenium supplements, exerts excellent antioxidant, antiviral, immunomodulatory, and other physiological functions mainly in the form of selenoprotein. The antiviral mechanism of SeMet anti-RSV was explored by detecting the apoptotic state, the degree of DNA damage, cytokine and reactive oxygen species (ROS) secretion levels, and the mitochondrial membrane potential. Meanwhile, this study screened the affinity of SeMet for common RSV target proteins and explored the dynamic interactions between SeMet and the screened viral target proteins.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.