Raman Spectroscopy and FRAP Analysis on Density Heterogeneity and Diffusion Behavior of Complex Coacervation by Arginine-Rich Dipeptides and Poly‑A RNA.

Ya Tian, Qiang Zhang, Jiangtao Li, Motosuke Tsutsumi, Tomoko Inose, Farsai Taemaitree, Kenji Hirai, Kohsuke Kanekura, Hiroshi Uji-I

Abstract read

PubMed Full text at PMC Publisher

In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ya TianResearch Institute for Electronic Science (RIES) and Division of Information Science and Technology, Hokkaido University, N20W10, Kita ward, Sapporo, Hokkaido 001-0020, Japan.

Qiang ZhangSchool of Medicine, Shihezi University, Shihezi 832003, China.

Jiangtao LiResearch Institute for Electronic Science (RIES) and Division of Information Science and Technology, Hokkaido University, N20W10, Kita ward, Sapporo, Hokkaido 001-0020, Japan.

Motosuke TsutsumiNational Institute for Physiological Sciences, National Institutes of Natural Sciences, 5-1 Higashiyama, Okazaki, Aichi 444-8787, Japan.

Tomoko InoseInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.ORCID https://orcid.org/0000-0003-2757-8817

Farsai TaemaitreeResearch Institute for Electronic Science (RIES) and Division of Information Science and Technology, Hokkaido University, N20W10, Kita ward, Sapporo, Hokkaido 001-0020, Japan.ORCID https://orcid.org/0000-0003-0295-9226

Kenji HiraiResearch Institute for Electronic Science (RIES) and Division of Information Science and Technology, Hokkaido University, N20W10, Kita ward, Sapporo, Hokkaido 001-0020, Japan.ORCID https://orcid.org/0000-0003-3307-3970

Kohsuke KanekuraDepartment of pharmacology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan.ORCID https://orcid.org/0000-0002-2901-9595

Hiroshi Uji-IResearch Institute for Electronic Science (RIES) and Division of Information Science and Technology, Hokkaido University, N20W10, Kita ward, Sapporo, Hokkaido 001-0020, Japan.ORCID https://orcid.org/0000-0002-0463-9659

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membraneless organelles (MLOs), formed through liquid-liquid phase separation (LLPS), are vital for various cellular functions, including gene expression and RNA metabolism. Destructions of LLPS dynamics, often due to aberrant condensate formation, are implicated in neurodegenerative diseases. Polypeptides composed of repeated dipeptides, namely arginine-rich dipeptide repeat proteins, poly-(proline-arginine) (poly-PR) and poly-(glycine-arginine) (poly-GR), translated from mutated

Identifiers

PMID40949254

DOI10.1021/acsomega.5c04844

PMCPMC12423859

What Socratic holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.