Evidence mapPaperPMID 40949364Full record

ReviewWorld journal of gastrointestinal surgery2025

Surgical treatment of colorectal cancer: A multidimensional review.

Jing-Xian Mao, Ran Gao, Ying Wang, Xue-Bing Yan, Hui-Hui Wang

Registry-linked trialAbstract readReview
In one paragraph

Review in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07529301 (The Effect of Functional Status and Respiratory Parameters on Early Postoperative Clinical Outcomes in Patients With Colorectal Cancer), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07529301 recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Functional Status and Respiratory Parameters on Early Postoperative Clinical Outcomes in Patients With Colorectal Cancer

Typeobservational_patient_registrySponsorMüşerref Ebru YALÇINRan2026 to 2027Enrolled42ConditionsColorectal Cancer, Functional Status, Respiratory Parameters, Clinical OutcomesArmsPreoperative Assessments, Postoperative Assessments (Daily from Postoperative Day 1 Until Discharge)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing-Xian MaoDepartment of Oncology, Affiliated Hospital of Yangzhou University, Yangzhou 225001, Jiangsu Province, China.
Ran GaoMedical College, Yangzhou University, Yangzhou 225001, Jiangsu Province, China.
Ying WangDepartment of Oncology, Affiliated Hospital of Yangzhou University, Yangzhou 225001, Jiangsu Province, China.
Xue-Bing YanSuining People's Hospital, Affiliated Hospital of Xuzhou Medical University, Xuzhou 225100, Jiangsu Province, China.
Hui-Hui WangMedical College, Yangzhou University, Yangzhou 225001, Jiangsu Province, China. wanghh56@yzu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the third most prevalent malignancy worldwide and the second leading cause of cancer-related mortality. Its global incidence increases annually, with most patients diagnosed at advanced stages. Despite substantial advancements in chemotherapy, radiotherapy, immune therapy, and targeted therapy, surgical treatment remains the mainstay for CRC management. Particularly, surgery is most effective for managing early-stage and locally advanced cancers. CRC surgery has evolved from conventional subtractive surgery to modern minimally invasive and precision-based techniques. Additionally, CRC treatment strategies have expanded from a single surgical therapy to a multi-modal integrated system encompassing endoscopic therapy, perioperative therapy, molecular targeted therapy, and immunotherapy. This review elucidates the evolution of CRC surgical treatment, describing its transition from early palliative surgery to radical surgery, and, finally, to functional surgery, minimally invasive surgical techniques, and personalized treatment. It reflects the transformation in CRC treatment from simplistic to complex, from generalized to precise, and from singular to comprehensive techniques, providing a holistic perspective on advancements in CRC surgical treatment.

Indexed as

Colorectal cancerComprehensive treatmentMultidisciplinary teamPrecision therapySurgical treatmentTargeted therapy

Identifiers

PMID40949364
PMCPMC12427049

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.