ReviewAmerican journal of translational research2025
Meta-analysis of the association between indoor environmental pollution and lung cancer risk in never-smokers.
Review in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Lung Cancer in Never-Smokers: Risk Factors, Driver Mutations, and Therapeutic Advances.Diagnostics (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis review systematically evaluates the association between indoor environmental pollution and lung cancer risk in never-smokers by meta-analysis, providing evidence-based prevention strategies for lung cancer.
methodsThis study was registered in PROSPERO (Registration No.: CRD420251008009) following the Preferred Reporting Items for Systematic Reviews and Meta - Analyses (PRISMA) guidelines. A systematic search was conducted in the PubMed, Web of Science, Embase, and Cochrane Library databases for relevant studies published from March 2005 to March 2025. Literature screening was conducted independently by two reviewers using a double-blind method. Study quality was assessed using the criteria recommended by the Agency for Healthcare Research and Quality (AHRQ). Meta-analysis was performed using STATA 12.0 and RevMan 5.3 software.
resultsA total of 22 studies met the inclusion criteria. Analysis showed that indoor environmental pollutants, including residential radon (Odds Ratio [OR] = 1.82, 95% CI: 1.31-2.54), environmental tobacco smoke (ETS) (OR = 1.96, 95% CI: 1.36-2.82), cooking fumes (OR = 3.68, 95% CI: 2.67-5.07), cooking methods (deep-frying: OR = 1.60, 95% CI: 0.72-3.52; stir-frying: OR = 1.12, 95% CI: 1.07-1.17), and the use of solid fuels (OR = 5.54, 95% CI: 3.15-9.72) were all significantly associated with an increased risk of lung cancer in non-smoking populations. In addition, the study found that residential environmental pollution, occupational exposures, and low body mass index (BMI) were also significant factors for lung cancer in non-smoking patients.
conclusionThis study confirmed that indoor environmental pollutants, including residential radon, ETS, cooking fumes, specific cooking methods (deep-frying and stir-frying), and the solid fuel use, are significantly associated with an increased risk of lung cancer in non-smoking populations. Furthermore, exposure to outdoor pollutants in residential areas and occupational environments cannot be ignored.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.