Evidence map›Paper›PMID 40951113›Full record

ArticleCureus2025

Clinical Value of 18F-Fluorodeoxyglucose (FDG) Positron Emission Tomography (PET)/Computed Tomography (CT) in Radioiodine-Refractory Thyroid Carcinoma: A Case Report.

David Gutiérrez Albenda, Laura N Rodríguez Varela, Julyana Murillo Jiménez, Paula Ulate Blanco, Juan J Solano Brenes

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David Gutiérrez AlbendaCyclotron-PET/CT Laboratory, University of Costa Rica, San José, CRI.
Laura N Rodríguez VarelaMedicine and Surgery, University of Costa Rica, San José, CRI.
Julyana Murillo JiménezMedicine and Surgery, University of Costa Rica, San José, CRI.
Paula Ulate BlancoMedicine and Surgery, University of Costa Rica, San José, CRI.
Juan J Solano BrenesMedicine and Surgery, University of Costa Rica, San José, CRI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioiodine-refractory differentiated thyroid cancer is a condition that arises in patients who develop resistance to the mainstay treatment for thyroid cancer. Although it is relatively uncommon, its clinical significance lies in the fact that it markedly worsens prognosis and calls for the implementation of alternative management strategies for affected patients. This is a case of a 40-year-old woman with a 17-year history of differentiated thyroid cancer, refractory to radioiodine (RAI), showing no iodine-131 uptake on whole body scan scintigraphy and elevated tumor markers. Through 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging, hypermetabolic foci were identified in the lungs, consistent with metastatic recurrent disease. Due to its effectiveness, 18F-FDG PET/CT should be considered for evaluation in cases of clinical suspicion in patients with elevated tumor markers and low iodine-131 uptake, consistent with radioiodine-refractory disease.

Indexed as

18f-fluorodeoxyglucosedifferentiated thyroid cancerpapillary thyroid carcinomapet ct scanthyroid radioiodine-refractory cancer

Identifiers

PMID40951113
PMCPMC12431828

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.