Observational studyJMIR aging2025
The Role of Physical Activity and Physical Function in Predicting Physical Frailty Transitions in Chinese Older Adults: Longitudinal Observational Study From CHARLS.
Observational study in JMIR aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Defining Frailty in Chinese-Language Biomedical Literature (2014-2024): A Decade of Conceptual Evolution.Aging medicine (Milton (N.S.W)) · 2026Review
- A digital platform-based stratified intervention for preventing disability risk in community-dwelling older adults: study protocol for a randomized multicenter trial.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Frailty is a dynamic geriatric syndrome associated with adverse health outcomes, yet its progression can be mitigated through targeted interventions. Objective: This study aimed to investigate predictors of frailty transitions in Chinese older adults, focusing on physical activity (PA) and physical function. Methods: Using data from the China Health and Retirement Longitudinal Study (CHARLS), we examined transitions between frailty states (robust, prefrail, and frail) from 2011 (baseline) to 2013 (follow-up) among 1014 participants aged 65 years and older. The following outcomes were assessed, including frailty using the physical frailty phenotype, PA using a modified International Physical Activity Questionnaire, and physical function using the Short Physical Performance Battery (SPPB) and handgrip strength. Ordinal logistic regression models were used to examine the relationship between PA, physical function, and frailty transitions. Results: Results showed that higher PA levels and better physical function reduced the likelihood of worsening frailty or increased the probability of transitioning to robustness. Key findings from the subgroup include: among robust individuals, greater handgrip strength predicted maintained robustness (average marginal effects [AME]=1.12%; P=.02); in prefrail individuals, higher vigorous PA (AME=21.76%; P=.04) and handgrip strength (AME=0.64%; P=.003) increased transitions to robustness; for frail individuals, increased low-intensity PA (AME =22.48%; P=.04) and higher SPPB walking subscores (AME=27.73%; P=.02) promoted improvement to nonfrailty. Conclusions: These findings highlight the importance of tailored interventions based on baseline frailty status. Promoting PA and improving physical function, particularly muscle strength and mobility function, may help delay or reverse frailty progression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.