Evidence map›Paper›PMID 40954952›Full record

ReviewGM crops & food2025

Multifaceted roles and regulatory mechanisms of MYB transcription factors in plant development, secondary metabolism, and stress adaptation: current insights and future prospects.

Muhammad Imran, Qiufei Wu, Chen Guanming, Lixia Zhou

Abstract readReview
In one paragraph

Review in GM crops & food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Plants (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. ComparativeFrontiers in plant science · 2026
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad ImranState Key Laboratory of Tropical Crop Breeding, Chinese Academy of Tropical Agricultural Sciences, Haikou, China.
Qiufei WuState Key Laboratory of Tropical Crop Breeding, Chinese Academy of Tropical Agricultural Sciences, Haikou, China.
Chen GuanmingSchool of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), School of Tropical Agriculture and Forestry, Hainan University, Sanya, China.
Lixia ZhouState Key Laboratory of Tropical Crop Breeding, Chinese Academy of Tropical Agricultural Sciences, Haikou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MYB transcription factor family represents one of the largest and most functionally diverse groups of regulatory proteins in plants, playing a crucial role in controlling genes involved in growth, development, and stress responses. MYB proteins are characterized by a conserved N-terminal DNA-binding domain. They are classified based on the number of R repeats, and possess a variable C-terminal region that determines their specific functions. In response to environmental signals, MYB proteins bind to specific DNA elements in target promoters, acting alone or with other regulators to modulate stress-responsive pathways. These factors integrate signaling cascades involving abscisic acid (ABA), jasmonic acid (JA), brassinosteroids (BR), and reactive oxygen species (ROS), aiding plant adaptation to adverse conditions. This review explores structural features, classification, and regulatory mechanisms, focusing on their roles in salinity, drought, extreme temperatures, nutrient deficiencies, heavy metal toxicity, and pathogen defense. Additionally, we highlight the advances and potential of MYB genes as targets for engineering stress-resilient crops through breeding and genetic modification.

Indexed as

Plant DevelopmentPlant ProteinsPlantsSecondary MetabolismTranscription FactorsAdaptation, PhysiologicalGene Expression Regulation, PlantPlant Growth RegulatorsStress, PhysiologicalPlant Growth RegulatorsPlant ProteinsTranscription FactorsDNA binding domainMYB geneplant stresstranscriptional regulation

Identifiers

PMID40954952
PMCPMC12445447

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.