Evidence map›Paper›PMID 40957680›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Involvement of the Endothelial

Alexandre Beranger, Morgane Lafenêtre, Sabrina Lacomme, Alexis Lebon, Damien Genty, Mélanie Brosolo, François Janin, Anaïs Leroy, Nicolas Guérout, Denis Vivien and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alexandre BerangerRouen University, Inserm UMR U1245 - Team "Epigenetics and Pathophysiology of Neurodevelopmental Disorders", Normandie University, Normandie Center for Genomic and Personalized Medicine, Rouen F-76000, France.
Morgane LafenêtreRouen University, Inserm UMR U1245 - Team "Epigenetics and Pathophysiology of Neurodevelopmental Disorders", Normandie University, Normandie Center for Genomic and Personalized Medicine, Rouen F-76000, France.
Sabrina LacommeUniv. Bordeaux, CNRS, INSERM, BIC, UAR 3420, Pessac F-33600, France.
Alexis LebonUniversity of Rouen Normandie, INSERM, CNRS, Normandie University, HeRacLeS US51, UAR2026, PRIMACEN, Rouen F-76000, France.
Damien GentyDepartment of Pathology, Rouen University Hospital, Rouen F-76000, France.
Mélanie BrosoloRouen University, Inserm UMR U1245 - Team "Epigenetics and Pathophysiology of Neurodevelopmental Disorders", Normandie University, Normandie Center for Genomic and Personalized Medicine, Rouen F-76000, France.
François JaninRouen University, Inserm UMR U1245 - Team "Epigenetics and Pathophysiology of Neurodevelopmental Disorders", Normandie University, Normandie Center for Genomic and Personalized Medicine, Rouen F-76000, France.
Anaïs LeroyRouen University, Inserm UMR U1245 - Team "Epigenetics and Pathophysiology of Neurodevelopmental Disorders", Normandie University, Normandie Center for Genomic and Personalized Medicine, Rouen F-76000, France.
Nicolas GuéroutSaints Pères Paris Institute for the Neurosciences, Paris Cité University, CNRS UMR8003, Paris F-75006, France.
Denis VivienUNICAEN, Inserm UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), GIP Cyceron, Blood and Brain Institute, Normandie University, Caen F-14074, France.ORCID 0000-0002-7636-2185
Ludovic GalasUniversity of Rouen Normandie, INSERM, CNRS, Normandie University, HeRacLeS US51, UAR2026, PRIMACEN, Rouen F-76000, France.
Stéphane MarretRouen University, Inserm UMR U1245 - Team "Epigenetics and Pathophysiology of Neurodevelopmental Disorders", Normandie University, Normandie Center for Genomic and Personalized Medicine, Rouen F-76000, France.
Florent MarguetRouen University, Inserm UMR U1245 - Team "Epigenetics and Pathophysiology of Neurodevelopmental Disorders", Normandie University, Normandie Center for Genomic and Personalized Medicine, Rouen F-76000, France.
Etienne GontierUniv. Bordeaux, CNRS, INSERM, BIC, UAR 3420, Pessac F-33600, France.
Bruno J GonzalezRouen University, Inserm UMR U1245 - Team "Epigenetics and Pathophysiology of Neurodevelopmental Disorders", Normandie University, Normandie Center for Genomic and Personalized Medicine, Rouen F-76000, France bruno.gonzales@univ-rouen.fr.ORCID 0000-0002-7176-1320
Maryline LecointreRouen University, Inserm UMR U1245 - Team "Epigenetics and Pathophysiology of Neurodevelopmental Disorders", Normandie University, Normandie Center for Genomic and Personalized Medicine, Rouen F-76000, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During cortical development, oligodendrocyte precursor (OPC) attachment and detachment to microvessels play a crucial role in their positioning and differentiation. In the developing brain, endothelial cells are regionally diverse, and previous studies showed a peak in cortical endothelial NMDA receptor (eNMDAR) expression during perinatal life, coinciding with OPC migration along microvessels. This raises the hypothesis that eNMDAR might influence the fate of vessel-associated OPC. In this study, a Grin1

Indexed as

Cell DifferentiationEndothelial CellsMicrovesselsMotor ActivityOligodendrogliaReceptors, N-Methyl-D-AspartateSensorimotor CortexAnimalsFemaleMaleMatrix Metalloproteinase 9MiceMice, Inbred C57BLMice, KnockoutNerve NetMatrix Metalloproteinase 9Mmp9 protein, mouseReceptors, N-Methyl-D-Aspartatecortexdevelopmentendothelial NMDA receptormotor disabilitiesoligodendrocyte

Identifiers

PMID40957680
PMCPMC12548711

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.