Evidence map›Paper›PMID 40958487›Full record

ArticleInfection & chemotherapy2025

Effectiveness and Safety of Bictegravir/Emtricitabine/Tenofovir Alafenamide in People with HIV in Korea: 24-Month Data from BICSTaR.

Yeon-Sook Kim, Jun Yong Choi, Dae Won Park, Shin-Woo Kim, Tae Hyong Kim, Julie Ryu, Rebecca Harrison, Jeong-A Lee, Flora Park, Sun Hee Lee

Abstract read
In one paragraph

Article in Infection & chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yeon-Sook KimDivision of Infectious Diseases, Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-1142-5488
Jun Yong ChoiDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2775-3315
Dae Won ParkDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea.ORCID https://orcid.org/0000-0002-7653-686X
Shin-Woo KimDivision of Infectious Diseases, Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-3755-8249
Tae Hyong KimDivision of Infectious Diseases, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-2920-9038
Julie RyuGilead Sciences, Inc., Foster City, CA, USA.ORCID https://orcid.org/0009-0002-9088-0883
Rebecca HarrisonReal World Solutions, IQVIA, London, UK.ORCID https://orcid.org/0000-0002-9765-8735
Jeong-A LeeGilead Sciences Korea Ltd, Seoul, Korea.ORCID https://orcid.org/0000-0001-7953-2357
Flora ParkGilead Sciences Korea Ltd, Seoul, Korea.ORCID https://orcid.org/0009-0007-8053-9397
Sun Hee LeeDepartment of Internal Medicine, Pusan National University School of Medicine and Medical Research Institute, Pusan National University Hospital, Busan, Korea. zzanmery@gmail.com.ORCID https://orcid.org/0000-0003-2093-3628

Funding

Gilead Sciences
6 · The paper itself

Abstract

BICtegravir Single Tablet Regimen is a multi-national observational cohort study evaluating the effectiveness and safety of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) in people with human immunodeficiency virus. We present 24-month data from participants in Korea. Eighty-eight participants (36 treatment-naïve [TN], 52 treatment-experienced [TE]) were included. At 24 months, 100% (29/29) of TN and 100% (37/37) of TE participants had HIV-1 RNA <50 copies/mL (missing=excluded analysis). BIC/FTC/TAF persistence was 100% (33/33) and 96.1% (49/51) in TN and TE participants, respectively. Drug-related adverse events occurred in 2 TN participants. Improvements in some patient-reported outcomes were observed. BIC/FTC/TAF maintained effectiveness, persistence, and tolerability over 24 months.

Indexed as

AsiaBictegravirCombination antiretroviral therapyKoreaObservational study

Identifiers

PMID40958487
PMCPMC12511748

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.