Evidence map›Paper›PMID 40958775›Full record

ReviewFrontiers in cellular neuroscience2025

NcRNAs: a potential treatment for spinal cord injury.

Jie Bao, Wenhui Zhi, Sheng Qi, Haolong Mo, Ruzhuan Liu, Chunhui Guo

Abstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Transcriptomics Insights into Spinal Cord Injury for Therapy Development.International journal of molecular sciences · 2026
    Review
  2. The role of epigenetic alterations in canine mammary cancer.The Journal of reproduction and development · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie BaoGraduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
Wenhui ZhiGraduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
Sheng QiGraduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
Haolong MoGraduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
Ruzhuan LiuRuikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
Chunhui GuoGraduate School, Guangxi University of Chinese Medicine, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal cord injury (SCI) is a serious disorder that affects sensory, motor, and autonomic functions. Its pathological process is divided into two stages: primary and secondary injury. The secondary injury involves a variety of biological cascade reactions, leading to an imbalance in the spinal cord microenvironment. Non-coding RNAs (ncRNAs) play a crucial regulatory role in the pathophysiological process of spinal cord injury, including long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs), all of which are involved in processes such as axonal regeneration, oxidative stress, inflammatory response, autophagy, and apoptosis. Although the pathophysiological process of spinal cord injury has been partially elucidated, its pathogenesis is not yet fully understood, and effective treatments are limited. This article reviews the regulatory role and molecular mechanisms of ncRNAs in the development and progression of spinal cord injury and proposes strategies for treating spinal cord injury by regulating ncRNAs.

Indexed as

circular RNAlong non-coding RNAmicroRNASCIspinal cord injury

Identifiers

PMID40958775
PMCPMC12433981

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.