Evidence mapPaperPMID 40959109Full record

ArticleJournal of Cancer2025

KDM6B enhances anti-PD-L1 immunotherapy efficacy by increasing CD8

Jing Xun, Zehan Liu, Bin Liu, Xiaolin Jiang, Huichao Yang, Jinjin Liu, Botao Wang, Ruifang Gao, Aimin Zhang, Xueliang Wu and 3 more

Abstract read
In one paragraph

Article in Journal of Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jing XunTianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100, China.
Zehan LiuDepartment of General Surgery, The Third People's Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University & The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu, China.
Bin LiuTianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100, China.
Xiaolin JiangTianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100, China.
Huichao YangTianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100, China.
Jinjin LiuTianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100, China.
Botao WangDepartment of Oncology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Ruifang GaoTianjin Institute of Medical and Pharmaceutical Sciences, Tianjin 300020, China.
Aimin ZhangTianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100, China.
Xueliang WuThe First Affiliated Hospital of Hebei North University, Hebei 075000, China.
Qing XiDepartment of Clinical Laboratory, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Xiangyang YuTianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100, China.
Qi ZhangTianjin Nankai Hospital, Tianjin Medical University, Tianjin 300100, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti-PD-L1CD8+ T cellscolorectal cancerlysine-specific demethylase 6B (KDM6B)tumor immunotherapy

Identifiers

PMID40959109
PMCPMC12435230

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.