Evidence map›Paper›PMID 40959140›Full record

ReviewFrontiers in cellular and infection microbiology2025

Mechanisms of fungal pathogenic DNA-activated STING pathway in biofilms and its implication in dental caries onset.

Yujie Zhou, Huanzhong Ji, Yuzhe Zhang, Yukun Liu, Yang Ning, Ping Li

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Imaging nucleic acids in biofilms.Essays in biochemistry · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yujie Zhou *Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China.
Huanzhong Ji *Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China.
Yuzhe ZhangHospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China.
Yukun LiuHospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China.
Yang NingHospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China.
Ping LiDepartment of Prosthodontics, School and Hospital of Stomatology, Guangzhou Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental caries, a prevalent oral disease, has long been attributed primarily to bacteria, but emerging evidence highlights the critical role of fungi in its pathogenesis. Fungal biofilms, predominantly

Indexed as

BiofilmsCandida albicansDental CariesDNA, FungalMembrane ProteinsAnimalsExtracellular VesiclesHost-Pathogen InteractionsHumansNucleotidyltransferasesSignal TransductionSTING ProteinDNA, FungalMembrane ProteinsNucleotidyltransferasesSTING1 protein, humanSTING Proteindental cariesextracellular DNAfungal biofilmsinnate immunitySTING pathway

Identifiers

PMID40959140
PMCPMC12434035

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.