Evidence map›Paper›PMID 40959207›Full record

ArticleMedComm2025

Butyrophilin 3A1 Contributes to Inflammation and Induces a Lupus-Like Disease by Inhibiting the IL-38-Ferroptosis Axis.

Wang-Dong Xu, Da-Cheng Wang, Yang-Yang Tang, Qi Huang, Lu Fu, You-Yue Chen, Lu-Qi Yang, Si-Yu Feng, Lin-Chong Su, An-Fang Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wang-Dong XuDepartment of Evidence-Based Medicine, School of Public Health Southwest Medical University Luzhou Sichuan China.
Da-Cheng WangDepartment of Evidence-Based Medicine, School of Public Health Southwest Medical University Luzhou Sichuan China.
Yang-Yang TangDepartment of Evidence-Based Medicine, School of Public Health Southwest Medical University Luzhou Sichuan China.
Qi HuangVanke School of Public Health Tsinghua University Beijing China.
Lu FuLaboratory Animal Center Southwest Medical University Luzhou Sichuan China.
You-Yue ChenDepartment of Evidence-Based Medicine, School of Public Health Southwest Medical University Luzhou Sichuan China.
Lu-Qi YangDepartment of Evidence-Based Medicine, School of Public Health Southwest Medical University Luzhou Sichuan China.
Si-Yu FengDepartment of Evidence-Based Medicine, School of Public Health Southwest Medical University Luzhou Sichuan China.
Lin-Chong SuHubei Provincial Key Laboratory of Occurrence and Intervention of Rheumatic Diseases Affiliated Minda Hospital of Hubei Minzu University Enshi Hubei China.
An-Fang HuangDepartment of Rheumatology and Immunology the Affiliated Hospital Southwest Medical University Luzhou Sichuan China.ORCID https://orcid.org/0000-0002-3860-8383

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown origin. Recent evidence has linked butyrophilin 3A1 (BTN3A1) to immune dysregulation. This study was to elucidate the relationship of BTN3A1 in SLE. Expression of BTN3A1 in plasma and peripheral blood mononuclear cells from SLE patients and healthy controls explored the association between BTN3A1 and SLE. We found that BTN3A1 mRNA, plasma levels, and expression in CD4

Indexed as

butyrophilin 3A1IL‐38inflammationlupus

Identifiers

PMID40959207
PMCPMC12433891

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.