ArticleJournal of experimental orthopaedics2025
High tibial osteotomy effectively restores motor function during daily activities in patients with knee osteoarthritis and varus deformity.
Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Sagittal alignment and patellofemoral consequences of open wedge high tibial osteotomy: a comparative radiological and gait analysis of supratubercle and distal tibial tuberosity techniques.Journal of orthopaedic surgery and research · 2026Article
- A long-term comparison of radiographic and clinical outcomes between 62% and 70% weight-bearing line targets in medial opening wedge high tibial osteotomy.Journal of experimental orthopaedics · 2026Article
- Altered gait strategies show inconsistent medial compartment unloading in varus medial knee osteoarthritis awaiting high tibial osteotomy.Clinical biomechanics (Bristol, Avon) · 2026Article
- Targeting subchondral osteoporosis in osteoarthritis: biomechanical crosstalk and the therapeutic rationale for inflammatory microenvironment remodeling.Frontiers in immunology · 2026Review
- Gait and plantar pressure changes after medial open-wedge high tibial osteotomy combined with arthroscopic partial meniscectomy.Frontiers in bioengineering and biotechnology · 2026Article
- High tibial osteotomy effectively restores motor function during daily activities in patients with knee osteoarthritis and varus deformity.Journal of experimental orthopaedics · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study evaluated the effects of high tibial osteotomy (HTO) on spatio-temporal parameters, kinematics and kinetics during walking, stair ascent and descent, in patients with medial knee osteoarthritis and varus malalignment, by using a prospective randomized case-control design, which compares the effects of HTO with a non-surgical conservative treatment. Methods: A total of 49 patients with medial knee osteoarthritis and varus malalignment were enroled in a prospective randomized case-control study. Patients were randomly assigned to the Surgical Group ( Results: In the Surgical Group, HTO significantly corrected the tibiofemoral angle (from 8.3 ± 3.3° to 0.9 ± 2.4°, Conclusions: HTO effectively restores knee alignment and major motor function parameters during walking and stair tasks, whereas non-surgical conservative treatments do not lead to any improvement. However, some residual motor function deviations persist after surgery, suggesting that certain biomechanical adaptations may remain after surgical correction. Level of Evidence: Level I, randomized controlled trial.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.