ReviewCureus2025
The Impact of Neonatal Sepsis on Long-Term Neurodevelopment: A Systematic Review of Cognitive and Sensory Outcomes.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Transforming central line associated blood stream infection prevention in neonates: Results from a multimodal quality improvement initiative.World journal of clinical pediatrics · 2026Article
- From Gram-Negative Neonatal Sepsis to Neurodevelopmental Impairment: A Retrospective Cohort Study in Preterm Infants.Children (Basel, Switzerland) · 2026Article
- Mitochondrial dysfunction in neonatal brain injury: from molecular mechanisms to therapeutic interventions.Journal of translational medicine · 2026Review
- MiR-181a, IL-6, and TNF-α: Biomarkers for Diagnosis and Long-Term Neurodevelopmental Prognosis in Neonatal Sepsis.Infection and drug resistance · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic review examines the long-term cognitive and sensory outcomes associated with neonatal sepsis. A comprehensive literature search was conducted in PubMed, Web of Science, Scopus, and Embase from January 2020 to July 2025, following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Studies were included if they reported neurodevelopmental outcomes among survivors of neonatal sepsis. A total of 14 eligible studies were identified and evaluated for risk of bias using the Newcastle-Ottawa Scale. Due to methodological heterogeneity, a narrative synthesis was performed. The included studies investigated a range of neurodevelopmental domains, with particular attention to cognitive, motor, and sensory outcomes. Findings varied across study populations and settings. Most studies reported a low risk of bias. This review highlights the need for standardized definitions of neonatal sepsis and outcome measures, as well as increased research focus on sensory outcomes and data from low-resource settings. Further prospective studies are recommended to enhance understanding of risk stratification and inform long-term follow-up strategies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.