ReviewIBRO neuroscience reports2025
The impact of perioperative hyperglycemia on postoperative cognitive function: A comprehensive review.
Review in IBRO neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyperglycemia, commonly triggered by the physiological stress of surgery, is exacerbated by counter-regulatory hormonal responses and can lead to significant complications including Postoperative Cognitive Dysfunction (POCD) and delirium. These conditions not only extend hospitalization and increase healthcare costs but also negatively impact long-term patient well-being. This review addresses multiple objectives by conducting a comprehensive literature review that synthesizes existing research across various surgical disciplines to assess the impact of hyperglycemia on cognitive outcomes. This involves integrating findings from both observational studies and clinical trials to offer a nuanced perspective on the current knowledge landscape. Secondly, it identifies significant gaps in research, including inconsistencies in outcomes and methodological shortcomings. Highlighting these gaps emphasizes the need for a more standardized approach to understanding hyperglycemia's cognitive effects post-surgery. Lastly, the review proposes future research directions, advocating for innovative research methodologies and clinical interventions aimed at mitigating the cognitive impairments associated with perioperative hyperglycemia. By providing an exhaustive examination of these aspects, the review seeks to enhance scholarly discourse and inform clinical practice, ultimately aiming to refine perioperative care protocols. This will protect cognitive functions and improve overall patient outcomes, bridging the gap between theoretical research and practical application, thereby setting the stage for advancements that could transform perioperative management standards.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.