Evidence map›Paper›PMID 40959572›Full record

ArticleInternational journal of medical sciences2025

Temporal Effects of Lipid Oversupply on Energy Metabolism and Mitochondrial Homeostasis in Hepatocytes.

Cheng-Chieh Chuang, Ying-Hao Chen, Fang-Yeh Chu, Ching-Ping Yang, Hsiang-Ling Ho, Fu-Pang Chang, Yu-Li Lo, Chun-Jung Chen, Yih-Hsin Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cheng-Chieh ChuangDepartment of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University, Taiwan.
Ying-Hao ChenDepartment of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University, Taiwan.
Fang-Yeh ChuDepartment of Clinical Pathology, Far Eastern Memorial Hospital, New Taipei City 220; Taiwan.
Ching-Ping YangDepartment of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University, Taiwan.
Hsiang-Ling HoDepartment of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University, Taiwan.
Fu-Pang ChangDepartment of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei 112; Taiwan.
Yu-Li LoDepartment and Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei 112; Taiwan.
Chun-Jung ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung 407; Taiwan.
Yih-Hsin ChangDepartment of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is closely associated with multiple metabolic disorders such as non-alcoholic fatty liver disease (NAFLD). Patients with NAFLD are susceptible to develop irreversible life-threatening diseases, however, the evolution concerning mitochondrial and metabolic alterations during NAFLD development and progression remain elusive. This study focused on uncovering the sequential events of energy metabolism and mitochondrial homeostasis of hepatocytes under the environment of lipid oversupply by

Indexed as

Energy MetabolismHepatocytesMitochondria, LiverNon-alcoholic Fatty Liver DiseaseAnimalsEpithelial-Mesenchymal TransitionFatty AcidsGlucoseHomeostasisHumansLipid MetabolismMaleMiceMitochondriaFatty AcidsGlucoseenergy metabolismhepatocyteslipid oversupplymitochondrial homeostasisobesity

Identifiers

PMID40959572
PMCPMC12434833

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.