SynthesisFrontiers in nutrition2025
The effects of magnesium and vitamin D/E co-supplementation on inflammation markers and lipid metabolism of obese/overweight population: a systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Magnesium: Hype and Health Benefits.Current nutrition reports · 2026Review
- The Role of the Gut Microbiota in Vascular Physiology and Health.International journal of molecular sciences · 2025Review
- Early Supplementation with Branched-Chain Amino Acids Ameliorates Lipid Retention in Aortic Valves of ApoE-Knockout Mice.International journal of molecular sciences · 2025Article
- Review
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
Background: Inflammatory reactions can induce or facilitate the occurrence and development of various diseases in the human body. It is crucial to regulate and actively control inflammatory factors to maintain the health of an individual. Vitamins D and E and magnesium ions may potentially inhibit inflammatory responses. Abnormal lipid metabolism is known to affect people's health and lead to serious diseases. Magnesium and vitamin E are also known to possess anti-lipidemic properties. It is worth noting that the prevalence and disease burden of some diseases are related to overweight and obesity. This systematic review and meta-analysis assesses the impact of magnesium and vitamin D or vitamin E co-supplementation on inflammation and lipid metabolism markers of obese/overweight population in randomized controlled trials (RCTs). Methods: A comprehensive search was conducted across PubMed, Web of Science, Embase and Cochrane databases until January 2024 to investigate the impact of simultaneous supplementation of magnesium and vitamin D/E. In both intervention and control groups, the research analyzed the pooled mean difference (MD) and the associated 95% confidence interval (CI) of marker levels of inflammation and lipid metabolism. Results: Meta-analysis of nine RCTs (total of 509 individuals) showed that magnesium and vitamin D significantly elevated the levels of 25(OH)D (MD:13.37, 95%CI: 0.45, 26.29, Conclusion: This study demonstrates a notable decrease in hs-CRP and TNF- Systematic review registration: https://www.crd.york.ac.uk/prospero/#loginpage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.