ReviewFrontiers in nutrition2025
The role of β-hydroxybutyrate testing in ketogenic metabolic therapies.
Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Trial
- A randomized safety and feasibility crossover trial of two Mediterranean-ketogenic interventions in individuals with Parkinson's disease.Journal of Parkinson's disease · 2026Trial
- KetoFLEX 12/3 Diet and Cognitive Health: A Precision-Nutrition Perspective on Mechanisms, Emerging Evidence, and Future Directions.Nutrients · 2026Review
- Effect of Oral Ketone Body Intake on Human CD8Nutrients · 2026Article
- Review
- Opinions on Ketogenic Diets Among Students and Academic Teachers at the University of Pécs, Hungary: A Cross-Sectional Survey.Nutrients · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate assessment of dietary adherence and metabolic outcomes remains a critical challenge in most nutrition studies. Ketogenic metabolic therapies (KMTs) provide a unique advantage by inducing nutritional ketosis and enabling the use of ketone bodies as biomarkers of metabolic state. This narrative review investigates the role of ketone testing as an integral component of KMTs. We introduce the key biomarkers and testing modalities currently used and present a comprehensive overview of the use of capillary blood β-hydroxybutyrate (BHB) testing across diverse therapeutic areas. Capillary blood BHB testing plays a multifaceted role in KMTs: it enables objective monitoring of dietary adherence, supports the interpretation of clinical outcomes, and informs personalized treatment adjustments based on individual metabolic responses. Additionally, it may facilitate behavior change through real-time feedback. Broader implementation of ketone testing in both clinical and research settings will require thoughtful protocol design that accounts for individual preferences and tolerability, continued technological innovation to enhance user experience, and further research into the relationship between ketone levels and therapeutic outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.