Evidence map›Paper›PMID 40960530›Full record

SynthesisSurgery today2025

Incidence of primary graft dysfunction and its associated risk factors after lung transplantation: a systematic review and meta-analysis.

Jing Pan, Jiejuan Zhang, Xiali Lu

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jing PanDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, No.37, Guoxue Lane, Wuhou District, Chengdu, 610041, Sichuan, China. panjing515@outlook.com.
Jiejuan ZhangDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, No.37, Guoxue Lane, Wuhou District, Chengdu, 610041, Sichuan, China.
Xiali LuDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, No.37, Guoxue Lane, Wuhou District, Chengdu, 610041, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This meta-analysis evaluates the prevalence of primary graft dysfunction (PGD) and its risk factors after lung transplantation (LT). We searched databases (PubMed, EMBASE, Cochrane Library, Web of Science) up until May, 2024. STATA 16 was used for data analysis. Random or fixed effects models were used to summarize the prevalence of PGD and associated risk factors according to statistical tests for heterogeneity. Risk of bias was assessed with the Newcastle-Ottawa Scale. A total of 61 studies with 59,865 patients were included. The pooled prevalence of grade 2 and grade 3 PGD was 27% (95% CI 0.19, 0.34) and 18% (0.16, 0.21), respectively. Donor-related risk factors included older age (OR = 1.04; 95% CI 1.00, 1.58), female gender (OR = 1.67; 95% CI 1.13, 2.48), and smoking history (OR = 1.84; 1.47, 2.30). Recipient factors were female gender (OR = 1.51; 95% CI 1.32, 1.74), higher BMI (OR = 1.22; 95% CI 1.11, 1.33), idiopathic pulmonary fibrosis (OR = 2.08; 95% CI 1.64, 2.63), and pulmonary hypertension (OR = 2.19; 95% CI 1.50, 3.21). Operative risks included higher reperfusion FiO

Indexed as

Lung TransplantationPrimary Graft DysfunctionAge FactorsFemaleHumansIncidenceMalePrevalenceRisk FactorsSex FactorsSmokingTissue DonorsLTLung transplantationMeta-analysisPGDPrimary graft dysfunction

Identifiers

PMID40960530

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.