Trial reportEuropean journal of applied physiology2026
Sex differences in beat-to-beat blood pressure variability following isometric handgrip exercise.
Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Saturation of muscle and peripheral oxygen, blood pressure, and perceived exertion in individuals exposed to repetitive muscle work.Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMTArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeIsometric handgrip (IHG) exercise lowers resting blood pressure (BP) and may modulate autonomic control, but its acute effects on beat-to-beat blood pressure variability (BPV) and sex-specific responses are unclear. We examined the impact of a single IHG bout on beat-to-beat BPV in healthy young adults, focusing on sex differences.
methodsThirty-eight subjects (20 men, 18 women) completed randomized, sham-controlled crossover trials: true IHG (30% MVC) and sham (3% MVC), each followed by 30 min of seated recovery. Continuous beat-to-beat BP, cardiac output (CO), and total peripheral resistance (TPR) were recorded. Variability was quantified via standard deviation (SD), range, interquartile range (IQR), coefficient of variation (CV), and average real variability (ARV).
resultsBeat-to-beat systolic blood pressure (SBP) variability showed marked sex- and time-dependent changes, with no trial-condition effects. In men, SBP SD rose from 6.2 ± 1.4 mmHg at rest to 6.7 ± 2.0 mmHg at 30 min (P < 0.05), whereas women's SD remained at 5.6 ± 1.4 to 5.1 ± 1.6 mmHg (P > 0.05; sex P = 0.018; time P = 0.024). Range and IQR followed SD rising in men at 30 min but stable in women (sex P = 0.022 and P = 0.037). CO ARV increased in men (239 ± 65 to 275 ± 75 mL/min; P < 0.05) but remained stable in women (224 ± 45 to 233 ± 61 mL/min; P > 0.05; sex × condition P = 0.026). TPR variability (SD, IQR, CV, ARV) exhibited a significant effect of time (P ≤ 0.002), with no differences between sexes or condition.
conclusionsA single IHG session does not acutely reduce beat-to-beat BPV in healthy young adults. Nevertheless, clear sex differences in beat-to-beat BPV responses highlight distinct autonomic and vascular regulation mechanisms.
Indexed as
Identifiers
40960641What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.