Evidence map›Paper›PMID 40960868›Full record

ArticleJournal of medical microbiology2025

Ozone water enema activates SIRT1-Nrf2/HO-1 pathway to ameliorate gut dysbiosis in mice receiving COVID-19 patient-derived faecal microbiota.

Zehua Su, Jiaqi Lin, Xuejiao Zeng, Xin Li, Qianhao Hou, Qing Wang, Chunzheng Liu, Jiawen Qin, Yuling Li, Jinyuan Zhang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zehua SuDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Jiaqi LinDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Xuejiao ZengDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Xin LiDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Qianhao HouDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Qing WangDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Chunzheng LiuDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Jiawen QinDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Yuling LiDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Jinyuan ZhangDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Xiangrui WangDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.
Shuwen QianDepartment of Anesthesiology and Pain Management, School of Medicine, Yangpu Hospital Affiliated To Tongji University, Shanghai 200090, PR China.
Lijun LiaoDepartment of Pain Management, School of Medicine, Shanghai East Hospital Affiliated To Tongji University, Shanghai 200120, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19DysbiosisEnemaGastrointestinal MicrobiomeHeme Oxygenase-1NF-E2-Related Factor 2OzoneSirtuin 1AnimalsDisease Models, AnimalFecal Microbiota TransplantationFecesFemaleHumansMaleMembrane ProteinsHeme Oxygenase-1Hmox1 protein, mouseMembrane ProteinsNfe2l2 protein, mouseNF-E2-Related Factor 2OzoneSirt1 protein, mouseSirtuin 1WaterCOVID-19gut microbiotaNrf2 (nuclear factor erythroid 2-related factor 2)/HO-1 (heme oxygenase-1)ozonated water enemaSIRT1(silent information regulator of transcription 1)

Identifiers

PMID40960868
PMCPMC12444790

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.