ArticleNeurology2025
Soccer Heading Exposure-Dependent Microstructural Injury at Depths of Sulci in Adult Amateur Players.
Article in Neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Cognitive and Behavioral Functioning in Female Former Soccer Players: Results from the Head Impact and Trauma Surveillance Study (HITSS).Brain sciences · 2026Article
- Soccer heading and white matter microstructural changes: a two-year longitudinal cohort study.Brain imaging and behavior · 2026Article
- Oral Contraceptives, Concussion History, and Contact-Sport Exposure: Multimodal MRI and Brain Injury Biomarkers in Female Athletes.Neurotrauma reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
BACKGROUND AND
objectivesRepetitive head impacts (RHIs) in sports are associated with adverse clinical and neuropathologic outcomes, but there is limited evidence from in vivo human imaging studies to inform risk assessment, exposure standards, and interventions. We tested the association of RHI with in vivo microstructural disruption at the depths of cerebral sulci, a region vulnerable to trauma.
methodsWe examined the relationship between soccer-related RHI exposure over 12 months and imaging measures. Participants included amateur soccer players and noncollision sport athletes aged 18-55 years from the Greater New York City area. We analyzed diffusion MRI measures specifically within the juxtacortical white matter at the depths of cortical sulci and crests of gyri, as well as within deep white matter. Cognitive function was assessed using components of the CogState computerized battery, focusing on verbal learning and memory performance.
resultsA total of 352 soccer players (mean [SD] age, 25.6 [7.5] years; 245 men [70%]) and 77 controls (22.8 [5.1] years; 30 men [39%]) were included. In multivariable regression, greater RHI was associated with lower fractional anisotropy (FA) (standardized β = -0.234; DISCUSSION: Higher RHI exposure was associated with MRI measures of microstructural disruption at the depths of sulci in an exposure-dependent manner. By contrast, deep white matter regions were relatively insensitive to RHI effects. Diffusion MRI at the depths of sulci may serve as a more specific marker of RHI-related brain injury.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.