Evidence map›Paper›PMID 40962949›Full record

ArticleSocial psychiatry and psychiatric epidemiology2026

From loneliness to depression: A longitudinal diagnostic study among Norwegian university students.

Mari Hysing, Keith J Petrie, Allison G Harvey, Børge Sivertsen

Abstract read
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Article in Social psychiatry and psychiatric epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Social Behavior and Neurogenesis.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mari HysingDepartment of Psychosocial Science, Faculty of Psychology, University of Bergen, Bergen, Norway. Mari.Hysing@uib.no.
Keith J PetrieDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
Allison G HarveyDepartment of Psychology, University of California, Berkeley, USA.
Børge SivertsenDepartment of Health Promotion, Norwegian Institute of Public Health, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLoneliness is an increasing public health concern among young adults. There is insufficient prior research on the association between loneliness and depressive disorder among students in higher education.

methodsThis prospective population-based cohort study from Norway invited all full-time students aged 18-35 to participate in the 2022 Students' Health and Wellbeing Study (SHoT). Of the 53,362 respondents, a subgroup of 16,418 students was randomly selected for diagnostic follow-up, with valid data from 10,460 participants. Loneliness was assessed in 2022 using the Three-Item Loneliness Scale (T-ILS) and Major Depressive Episodes (MDE) were assessed in 2023 using a self-administered electronic version of the Composite International Diagnostic Interview, version 5.0 (CIDI 5.0).

resultsA clear dose-response relationship was observed: students in the highest loneliness quintile had a substantially increased risk of MDE one year later. After adjusting for age and baseline anxiety and depression symptoms, the relative risk (RR) for MDE in the highest versus lowest T-ILS quintile was 2.02 (95% CI: 1.58-2.63) for females and 2.64 (95% CI: 1.63-4.49) for males-representing a ~ 70-75% reduction from unadjusted estimates. The overall prevalence of MDE was 21.1% in females and 11.2% in males. Formal interaction analyses indicated a statistically significant multiplicative interaction by sex, but no evidence of additive interaction.

conclusionsLoneliness is a strong and independent predictor of MDE in young adults, even after accounting for baseline mental health. Targeting loneliness may be important for preventing depression in university populations.

Indexed as

DepressionLonelinessMajor Depressive DisorderStudentsAdolescentAdultFemaleHumansLongitudinal StudiesMaleNorwayProspective StudiesRisk FactorsUniversitiesYoung AdultDepressionHigher educationLonelinessStudentsYoung adults

Identifiers

PMID40962949
PMCPMC12995926

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.