Evidence map›Paper›PMID 40963907›Full record

ArticleTheranostics2025

Targeted autophagic clearance of Tau protects against Alzheimer's disease through amelioration of Tau-mediated lysosomal stress.

Bo Hyun Yoon, Jinho Kim, Sandip Sengupta, Chan-Jung Park, Minjoo Ko, Ji Hee Kang, Young Tag Ko, Yeji Kim, Seung Min Lim, Yoonhee Bae and 8 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Compartmental pH regulation in cancer and antitumor immunity: therapeutic opportunities and challenges.Apoptosis : an international journal on programmed cell death · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Bo Hyun YoonSoonchunhyang Institute of Medi-bio Science, Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
Jinho KimDept. of Pharmacology, College of Medicine, GAIHST, Gachon University, Incheon, Korea.
Sandip SenguptaDepartment of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Korea.
Chan-Jung ParkDepartment of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Korea.
Minjoo KoDepartment of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Korea.
Ji Hee KangCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon, Korea.
Young Tag KoCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon, Korea.
Yeji KimDept. of Pharmacology, College of Medicine, GAIHST, Gachon University, Incheon, Korea.
Seung Min LimDept. of Pharmacology, College of Medicine, GAIHST, Gachon University, Incheon, Korea.
Yoonhee BaeSoonchunhyang Institute of Medi-bio Science, Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
MooYoung ChoiDepartment of Physics and Center for Theoretical Physics, Seoul National University, Seoul, Korea.
Yunyeong JangChemical Genomics Leader Research Laboratory and Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul, Korea.
Ho Jeong KwonChemical Genomics Leader Research Laboratory and Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul, Korea.
Hyo Jin SonDept. of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Hee Jin KimDept. of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Taebo SimDepartment of Biomedical Sciences, Yonsei University College of Medicine, Seoul, Korea.
Keun-A ChangDept. of Pharmacology, College of Medicine, GAIHST, Gachon University, Incheon, Korea.
Myung-Shik LeeSoonchunhyang Institute of Medi-bio Science, Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseAutophagyLysosomestau ProteinsAmyloid beta-PeptidesAnimalsDisease Models, AnimalHumansInduced Pluripotent Stem CellsMiceMice, TransgenicNeuronsAmyloid beta-Peptidestau ProteinsAlzheimer's diseaseautophagylysosomal stressspecificityTau

Identifiers

PMID40963907
PMCPMC12439469

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.