ArticleBreathe (Sheffield, England)2025
The road less travelled: thoracic ultrasound, advanced imaging and artificial intelligence for early diagnosis of non-expandable lung in malignant pleural effusion.
Article in Breathe (Sheffield, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Ultrasound Techniques for Suspected Malignant Pleural Effusion and Nonexpandable Lung.CHEST pulmonary · 2026Review
- Thoracic ultrasound elastography in pleural and subpleural diseases: a narrative review.Journal of ultrasound · 2026Review
- Artificial Intelligence-Induced Deskilling in Interventional Pulmonology: An International Cross-Sectional Survey on Risk Perception and Mitigation Strategies.Advances in respiratory medicine · 2026Observational
- Artificial intelligence for pleural effusion and pneumothorax detection on thoracic ultrasound: an educational viewpoint on the promise, pitfalls and path forward.Breathe (Sheffield, England) · 2026Article
- The price of immune awakening: bridging knowledge gaps in checkpoint inhibitor-related pneumonitis in lung cancer.Breathe (Sheffield, England) · 2026Article
- Highlights from the Italian National Congress of Imaging in Pulmonology 2025: fostering implementation of advanced technologies for precision patient-centered care.Multidisciplinary respiratory medicine · 2026Article
- Artificial Intelligence-Based Automated Analysis for Pleural Effusion Detection on Thoracic Ultrasound: A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Decoding the "black-box": explainable artificial intelligence towards trustworthy advancement in respiratory medicine.Breathe (Sheffield, England) · 2026Article
- Exploring pleural effusion characterisation with quantitative thoracic ultrasound imaging: a viewpoint on the investigational role of pixel-based echogenicity analysis in transudate and exudate differentiation.Breathe (Sheffield, England) · 2025Article
- Intercostal Artery Screening with Color Doppler Thoracic Ultrasound in Pleural Procedures: A Potential Yet Underexplored Imaging Modality for Minimizing Iatrogenic Bleeding Risk in Interventional Pulmonology.Journal of clinical medicine · 2025Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant pleural effusion (MPE) affects up to 15% of cancer patients, with nearly 30% of symptomatic cases developing non-expandable lung (NEL), a condition characterised by the lung's failure to fully re-expand post-drainage, thereby impeding proper pleural apposition and leading to several adverse outcomes. Inadequate diagnostic certainty leads to prolonged hospitalisation, repeated invasive procedures, drainage complications, high pleurodesis failure rates, increased healthcare costs and diminished patient quality of life. Conventional diagnostic methods, predominantly based on post-procedural chest radiography and computed tomography, frequently delay accurate diagnosis, underscoring the need for noninvasive pre-procedural techniques. Emerging evidence supports thoracic ultrasound, particularly the application of M-mode during breath-hold, as a promising modality for early NEL detection by identifying the absent sinusoidal sign and reduced lung movement. Experimental approaches, including speckle tracking imaging, two-dimensional shear wave elastography and quantitative ultrasound assessments
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.