Evidence map›Paper›PMID 40964227›Full record

ReviewSleep science (Sao Paulo, Brazil)2025

Unlocking Mysteries: Exploring the Dynamic Interplay Among Sleep, the Immune System, and Curcumin in Contemporary Research.

Rohit Kumar, Atul Pandey, Arpana Vibhuti, Manzoor Ali, Chung-Ming Chang, Ramendra Pati Pandey

Abstract readReview
In one paragraph

Review in Sleep science (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rohit KumarDepartment of Biotechnology, Sri Ramaswamy Memorial (SRM) University, Sonipat, Haryana, India.
Atul PandeyDepartment of Ecology and Evolutionary Biology, College of Literature, Science, and the Arts, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0001-6954-6990
Arpana VibhutiDepartment of Biotechnology, Sri Ramaswamy Memorial (SRM) University, Sonipat, Haryana, India.
Manzoor AliGenomics and Genome Biology Unit, Council of Scientific and Industrial Research, Institute of Genomics and Integrative Biology, Delhi, India.
Chung-Ming ChangChang Gung University, Guishan Dist, Taoyuan City, Taiwan.
Ramendra Pati PandeyDepartment of Biotechnology, Sri Ramaswamy Memorial (SRM) University, Sonipat, Haryana, India.ORCID 0000-0002-5196-6468

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The scientific disciplines encompassing sleep, the immune system, and curcumin have garnered considerable interest due to their interconnectedness and potential implications for human health. Sleep is a crucial factor in maintaining optimal immune function, as it facilitates the release of cytokines, which are signaling molecules responsible for regulating immune responses. On the contrary, sleep deprivation has the potential of inhibiting immune function, thereby heightening the susceptibility to infection and disease. Curcumin, a naturally occurring polyphenol derived from the turmeric plant, has been observed to possess immunomodulatory characteristics through its ability to modulate the equilibrium between pro- and anti-inflammatory cytokines. It is worth noting that there is evidence suggesting that curcumin supplementation could enhance the quality of sleep. Scientific studies have indicated that curcumin supplementation has been associated with an increase in the duration of sleep and a decrease in wakefulness among individuals who are in good health. Additionally, curcumin supplementation has been found to enhance sleep quality and alleviate symptoms of depression in individuals diagnosed with major depressive disorder. The intricate interplay among sleep, the immune system, and curcumin is multifaceted, and scientific investigations indicate that curcumin may serve as a beneficial dietary adjunct to enhance immune function and optimize sleep quality. Nevertheless, additional investigation is required to fully comprehend the mechanisms through which curcumin alters the immune system and enhances sleep, as well as to ascertain the most effective dose and timing of curcumin supplementation.

Indexed as

curcumincytokinesneuro-inflammationNREM sleepREM sleepsleep loss

Identifiers

PMID40964227
PMCPMC12440604

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.