ReviewSleep science (Sao Paulo, Brazil)2025
Unlocking Mysteries: Exploring the Dynamic Interplay Among Sleep, the Immune System, and Curcumin in Contemporary Research.
Review in Sleep science (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The scientific disciplines encompassing sleep, the immune system, and curcumin have garnered considerable interest due to their interconnectedness and potential implications for human health. Sleep is a crucial factor in maintaining optimal immune function, as it facilitates the release of cytokines, which are signaling molecules responsible for regulating immune responses. On the contrary, sleep deprivation has the potential of inhibiting immune function, thereby heightening the susceptibility to infection and disease. Curcumin, a naturally occurring polyphenol derived from the turmeric plant, has been observed to possess immunomodulatory characteristics through its ability to modulate the equilibrium between pro- and anti-inflammatory cytokines. It is worth noting that there is evidence suggesting that curcumin supplementation could enhance the quality of sleep. Scientific studies have indicated that curcumin supplementation has been associated with an increase in the duration of sleep and a decrease in wakefulness among individuals who are in good health. Additionally, curcumin supplementation has been found to enhance sleep quality and alleviate symptoms of depression in individuals diagnosed with major depressive disorder. The intricate interplay among sleep, the immune system, and curcumin is multifaceted, and scientific investigations indicate that curcumin may serve as a beneficial dietary adjunct to enhance immune function and optimize sleep quality. Nevertheless, additional investigation is required to fully comprehend the mechanisms through which curcumin alters the immune system and enhances sleep, as well as to ascertain the most effective dose and timing of curcumin supplementation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.