Evidence mapPaperPMID 40964671Full record

ArticleFrontiers in microbiology2025

Changes in the gut microbiome of older adults according to hypertension control.

Fernanda Valdez-Palomares, Tomas Texis, Sergio Sánchez-García, José Darío Martínez-Ezquerro, Paola García-de la Torre, Mauricio Rodríguez-Dorantes, Alma Genis-Mendoza, Salvador Fabela, Berenice Palacios-González, Vanessa González-Covarrubias

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Foods (Basel, Switzerland) · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fernanda Valdez-Palomares *Instituto Nacional de Medicina Genómica (INMEGEN), CDMX, Mexico City, Mexico.
Tomas Texis *Instituto Nacional de Medicina Genómica (INMEGEN), CDMX, Mexico City, Mexico.
Sergio Sánchez-GarcíaUnidad de Investigación Epidemiológica y en Servicios de Salud, Área Envejecimiento, Centro Médico Nacional Siglo XXI, Instituto Nacional del Seguro Social (IMSS), CDMX, Mexico City, Mexico.
José Darío Martínez-EzquerroUnidad de Investigación Epidemiológica y en Servicios de Salud, Área Envejecimiento, Centro Médico Nacional Siglo XXI, Instituto Nacional del Seguro Social (IMSS), CDMX, Mexico City, Mexico.
Paola García-de la TorreUnidad de Investigación Epidemiológica y en Servicios de Salud, Área Envejecimiento, Centro Médico Nacional Siglo XXI, Instituto Nacional del Seguro Social (IMSS), CDMX, Mexico City, Mexico.
Mauricio Rodríguez-DorantesInstituto Nacional de Medicina Genómica (INMEGEN), CDMX, Mexico City, Mexico.
Alma Genis-MendozaInstituto Nacional de Medicina Genómica (INMEGEN), CDMX, Mexico City, Mexico.
Salvador FabelaInstituto Nacional de Medicina Genómica (INMEGEN), CDMX, Mexico City, Mexico.
Berenice Palacios-GonzálezInstituto Nacional de Medicina Genómica (INMEGEN), CDMX, Mexico City, Mexico.
Vanessa González-CovarrubiasInstituto Nacional de Medicina Genómica (INMEGEN), CDMX, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is the leading cause of cardiovascular disease, with over 60% prevalence in older adults, and its control is complex and requires multidisciplinary approaches. The role of the gut microbiome in blood pressure control remains unclear despite reported associations of some specific bacteria involved in the development of hypertension. The aim of this study was to characterize the gut microbiome of older adults and to identify bacteria associated with hypertension control. Patients aged 60 years and older from Mexico City and the metropolitan area, all of whom were receiving antihypertensive treatment, provided a feces sample during a routine medical visit. DNA was extracted from 240 samples using a commercial kit, the V3/V4 region of the 16S gene was sequenced, and metataxonomic analyses were performed using QIIME and R. Bacterial abundance analysis identified a core microbiome in the hypertensive older adults, with an increased abundance of

Indexed as

diastolic blood pressuregut microbiomehypertensionolder adultssystolic blood pressure

Identifiers

PMID40964671
PMCPMC12438838

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.