Evidence map›Paper›PMID 40965061›Full record

ReviewMini reviews in medicinal chemistry2025

Extraction, Physicochemical Properties, and Biomedical Applications of Locust Bean Gum: A Comprehensive Review.

Deepak Kumar, Rishabha Malviya, Sathvik Belagodu Sridhar, Javedh Shareef, Tarun Wadhwa

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mini reviews in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Deepak KumarDepartment of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, U.P., India.
Rishabha MalviyaDepartment of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, U.P., India.ORCID 0000-0003-2874-6149
Sathvik Belagodu SridharRAK College of Pharmacy, RAK Medical & Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Javedh ShareefRAK College of Pharmacy, RAK Medical & Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Tarun WadhwaRAK College of Pharmacy, RAK Medical & Health Sciences University, Ras Al Khaimah, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Locust bean gum (LBG), a naturally derived polysaccharide from Ceratonia siliqua, exhibits high biocompatibility, degradability, and gel-forming capability, making it a potential contender for pharmaceutical applications. It has wide applications in drug delivery as well as wound healing because of its physicochemical characteristics, including mucoadhesive properties, swelling capability, and controlled release. This study explores the role of LBG-based composites in controlled drug release and wound dressing applications. LBG has been broadly used for drug delivery by oral, transdermal, and mucosal routes. Its mucoadhesive properties increase drug uptake, while gelation facilitates controlled and sustained drug release. Crosslinking and carboxymethylation have been used to improve its functional properties, and it has been utilised in targeted and responsive delivery systems. LBG-based hydrogels and films have also been developed for wound healing and have shown moisture retention, antimicrobial activity, and biocompatibility. Smart wound dressings with LBG and bioactive agents have enabled real-time infection monitoring with enhanced tissue regeneration. Studies have proven that LBG can improve the mechanical strength and drug-loading capacity of composite materials and is hence a potential candidate for next-generation biomedical applications. LBG-based composites hold significant potential in pharmaceuticals, particularly in wound healing and drug delivery.

Indexed as

GalactansMannansPlant GumsAnimalsDrug Delivery SystemsHumansHydrogelsWound HealingGalactansHydrogelslocust bean gumMannansPlant GumsbiocompatibilitybiomaterialsCarob seed gumcontrolled drug releasegalactomannanhydrogelswound dressings.wound healing

Identifiers

PMID40965061

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.