Evidence map›Paper›PMID 40965130›Full record

ArticleJournal of the American Chemical Society2025

Hydration (H

Carter Lantz, Robert L Rider, Syuan-Ting Kuo, Zhenyu Xi, Emily Burningham, Sangho D Yun, Arthur Laganowsky, David H Russell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carter LantzDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Robert L RiderDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0002-7894-4920
Syuan-Ting KuoDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Zhenyu XiDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Emily BurninghamDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Sangho D YunDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Arthur LaganowskyDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0001-5012-5547
David H RussellDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0003-0830-3914

Funding

Understanding the role of lipids in structure and function of membrane proteinsRM1GM145416 · NIGMS · TEXAS A&M UNIVERSITY · PI Erin S Baker, Arthur D Laganowsky · 2022 to 2026
$7.4M
Native Mass Spectrometry Guided Structural Biology CenterRM1GM149374 · NIGMS · OHIO STATE UNIVERSITY · PI Vicki H. Wysocki · 2023 to 2026
$5.0M
Innovative Native Ion Mobility Approaches for Transformational Measurements in Structural BiologyR01GM138863 · NIGMS · TEXAS A&M UNIVERSITY · PI CLOWERS, BRIAN, LAGANOWSKY, ARTHUR D · 2020 to 2023
$1.2M
NIGMS NIH HHS R01 GM138863NIGMS NIH HHS RM1 GM145416NIGMS NIH HHS RM1 GM149374
6 · The paper itself

Abstract

Transthyretin (TTR) is a 56 kDa tetrameric protein complex that plays a key role in transporting thyroxine and retinol. Despite its important biological role, TTR exhibits adverse effects, including disassembly into monomers, dimers, and trimers that then aggregate into disease-causing oligomers and fibrils. Hydration (referring to H

Indexed as

Deuterium OxideEntropyPrealbuminWaterHumansProtein ConformationProtein MultimerizationProtein StabilityDeuterium OxidePrealbuminWater

Identifiers

PMID40965130
PMCPMC12498396

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.