Evidence mapPaperPMID 40965250Full record

SynthesisAnnals of medicine2025

Association of body mass index and bone mineral density in postmenopausal women: a systematic review and meta-analysis.

Sijia Cai, Jingtao Gao, Chengli Li, Feiqi Lu, Dong Hu, Xiaobin Luo, Zhe Zhao, Yongwei Pan, Guman Duan

Erratum issuedAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sijia CaiDepartment of Endocrinology, Beijing Hepingli Hospital, Beijing, China.ORCID 0009-0000-3511-4639
Jingtao GaoOrthopedics & Sports Medicine Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Chengli LiOrthopedics & Sports Medicine Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Feiqi LuOrthopedics & Sports Medicine Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Dong HuOrthopedics & Sports Medicine Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Xiaobin LuoOrthopedics & Sports Medicine Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.ORCID 0000-0003-0859-4723
Zhe ZhaoOrthopedics & Sports Medicine Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.ORCID 0000-0001-5959-9941
Yongwei PanOrthopedics & Sports Medicine Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.ORCID 0000-0002-0456-9523
Guman DuanOrthopedics & Sports Medicine Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.ORCID 0000-0002-9888-7345

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis meta-analysis aims to exploring the correlation between body mass index (BMI) and bone mineral density (BMD) in postmenopausal women (PMW).

methodsThe MEDLINE, Embase, Web of Science, Scopus and Cochrane Central database was searched in August 2025. Special medications or diseases were excluded, and the correlation coefficient values of BMI and BMD within different bone regions were extracted and pooled. Sensitivity and meta-regression analysis were further investigated. This study was pre-registered in PROSPERO (CRD42024550020).

resultsTwenty nine studies from 19 countries were analyzed, involving 9,086 PMW whose mean age ranged between 53.3 and 70.2 years. Sufficient data supported a positive correlation between BMI and BMD within PMW. The pooled Pearson r for the whole-body was 0.355 (95% CI: 0.269, 0.440) with heterogeneity (I

conclusionA positive correlation between the BMD and BMI in PMW with various degrees. Trochanteric sites had the largest correlation, calcaneal sites had the lowest correlation, while other sites were moderate. Efforts to limit decreasing of BMI preventing BMD decreasing in PMW were reasonable.

Indexed as

Body Mass IndexBone DensityOsteoporosis, PostmenopausalPostmenopauseAgedFemaleFemur NeckHumansMiddle Agedbody mass indexbone mineral densitymeta-analysisobesityosteoporosisPostmenopausalsystematic review

Identifiers

PMID40965250
PMCPMC12447469

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.