Unraveling the Inactivation Mechanisms of Human Adenovirus 2 in Sunlight Disinfection: Synergism between Direct and Indirect Pathways.

Abstract read

In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Rapid Solar Photoinactivation of Influenza Virus and Phi6 in Colored Surface Water.Environmental science & technology · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sujin ShinDepartment of Environment and Energy Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea.ORCID 0000-0003-4351-5277

Yunho LeeDepartment of Environment and Energy Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Republic of Korea.ORCID 0000-0001-5923-4897

Tamar KohnLaboratory of Environmental Virology, School of Architecture, Civil and Environmental Engineering, Swiss Federal Institute of Technology in Lausanne (EPFL), Lausanne 1015, Switzerland.ORCID 0000-0003-0395-6561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenovirus (HAdV), a double-stranded DNA virus, exhibits resistance to direct inactivation by UVC and solar UVB radiation in water, owing to its ability to repair UV-induced genome damage using host cellular machinery. In the presence of dissolved organic matter (DOM), however, previous studies have reported unexpectedly rapid sunlight-mediated inactivation, even after accounting for indirect effects mediated by photochemically produced reactive intermediates (PPRIs). Here, we hypothesized that a synergistic interaction between direct and indirect inactivation pathways compromises HAdV2's genome repair capacity, thereby enhancing its overall susceptibility to inactivation. First, we demonstrated that pre-exposure to singlet oxygen (

Indexed as

Adenoviruses, HumanDisinfectionSunlightDNA DamageHumansUltraviolet RaysVirus InactivationGenome repairHuman adenovirusRepair-deficient cellsSunlight disinfectionSynergism

Identifiers

PMID40966025

DOI10.1021/acs.est.5c06149

PMCPMC12490006

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.