Evidence mapPaperPMID 40966651Full record

ReviewBriefings in bioinformatics2025

Artificial intelligence for comprehensive DNA methylation analysis: overview, challenges, and future directions.

Aymane Aghziel, Mohamed Adnane Mahraz, Hamid Tairi, Noura Aherrahrou

Abstract readReview
In one paragraph

Review in Briefings in bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aymane AghzielL3IA Laboratory, Department of Computer Science, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796 - Atlas, 30003, Fez, Morocco.
Mohamed Adnane MahrazL3IA Laboratory, Department of Computer Science, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796 - Atlas, 30003, Fez, Morocco.
Hamid TairiL3IA Laboratory, Department of Computer Science, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796 - Atlas, 30003, Fez, Morocco.
Noura AherrahrouL3IA Laboratory, Department of Computer Science, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796 - Atlas, 30003, Fez, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper offers a comprehensive review of the synergy between artificial intelligence and DNA methylation analysis, encompassing machine learning, deep learning, natural language processing, and explainable artificial intelligence. In this study, we also highlighted the underexplored potential of signal processing and large language models-based models in DNA methylation research. Additionally, we discussed the challenges and limitations faced when managing and analyzing large and complex DNA methylation datasets. Furthermore, this article tries to shed light on the continuing evolution of this field and on the possible directions for future research.

Indexed as

Artificial IntelligenceDNA MethylationComputational BiologyDeep LearningHumansMachine LearningNatural Language ProcessingAIDNA methylationLLMsNLPsignal processingXAI

Identifiers

PMID40966651
PMCPMC12448452

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.