Evidence map›Paper›PMID 40967760›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Assessment of Breast Tumors Using Multispectral Optoacoustic Tomography in a Surgical Setting.

Lacey R McNally, Juan Carlos Claros-Sorto, Ryan C Bynum, William E Grizzle, Zheng Han, Ronald Squires, Jacob D Tippetts, Andrew Brannen, Tabitha Garwe, Andrew Cohoon and 3 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lacey R McNallyDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma; lacey_mcnally@hotmail.com ajay-jain@ouhsc.edu.
Juan Carlos Claros-SortoDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma.
Ryan C BynumDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma.
William E GrizzleDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama.
Zheng HanDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma.
Ronald SquiresDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma.
Jacob D TippettsiTheraMedical, Boston, Massachusetts.
Andrew BranneniTheraMedical, Boston, Massachusetts.
Tabitha GarweDepartment of Biostatistics, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma; and.
Andrew CohoonDepartment of Biostatistics, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma; and.
Barish H EdilDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma.
Jennifer Holter-ChakrabartyDepartment of Internal Medicine, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma.
Ajay JainDepartment of Surgery, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma; lacey_mcnally@hotmail.com ajay-jain@ouhsc.edu.

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ROBERT S. MANNEL · 2018 to 2026
$27.1M
TRAINING AND CAREER DEVELOPMENTU54CA118948 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI UPENDER MANNE, Erica Michelle Stringer-Reasor · 2005 to 2026
$26.6M
Development of contrast agents to facilitate image-guided surgeryR01CA281098 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI JAIN, AJAY, MCNALLY, LACEY R · 2023 to 2025
$2.9M
Development of an apoptosis biosensor for monitoring of breast cancerR01EB034731 · NIBIB · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HENARY, MAGED M, MCNALLY, LACEY R · 2023 to 2025
$1.5M
NCI NIH HHS P30 CA225520NCI NIH HHS R01 CA281098NCI NIH HHS U54 CA118948NIBIB NIH HHS R01 EB034731
6 · The paper itself

Abstract

In breast-conserving surgery, wire or seed localization and ultrasound are limited by lack of margin detection and contrast imaging, respectively. Handheld multispectral optoacoustic tomography (MSOT) allows for contrast imaging using endogenous or exogenous agents. This trial evaluated the safety and performance of MSOT for imaging breast masses intraoperatively.

Indexed as

Breast NeoplasmsPhotoacoustic TechniquesAdultAgedFemaleHumansMiddle Agedbreast cancerbreast-conserving therapyFitzpatrick skin typeoptoacoustic imagingphotoacoustic imaging

Identifiers

PMID40967760
PMCPMC12487731

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.