Evidence map›Paper›PMID 40967819›Full record

ArticlePolish journal of microbiology2025

Oral Microbiota and Pharyngeal-Laryngeal Cancer Risk: Evidence from Mendelian Randomization in East Asian Populations.

Jingfeng Fu

Abstract read
In one paragraph

Article in Polish journal of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jingfeng FuSchool of Pharmacy and Medical Technology, Putian University, Putian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharyngeal and laryngeal cancer (PLC) encompasses a range of aggressive malignancies associated with substantial clinical impact, underscoring the need for novel preventive and therapeutic measures. Mendelian randomization (MR) serves as an effective methodology for assessing causal associations based on genetic variants as instrumental tools. It reduces biases such as confounding and reverse causation prevalent in traditional observational studies. This research sought to investigate the causal relationships between oral microbial taxa and PLC using a two-sample MR approach. The goal was to identify specific oral microbiota that may directly contribute to the development of PLC and could serve as potential biomarkers or targets for therapeutic intervention. A two-sample MR analysis was conducted to assess the causal impact of 3,117 oral microbial taxa on the risk of PLC. Instrumental variables (IVs) were selected based on genome-wide significance (

Indexed as

Laryngeal NeoplasmsMicrobiotaMouthPharyngeal NeoplasmsAsia, EasternEast Asian PeopleHumansMendelian Randomization AnalysisRisk FactorsGWASMendelian randomizationoral microbiotapharyngeal and laryngeal cancer

Identifiers

PMID40967819
PMCPMC12445983

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.