Evidence map›Paper›PMID 40968188›Full record

ArticlePediatric cardiology2026

Influence of Heart Rate on Hemodynamics in Fontan Circulation.

Aya Miyazaki, Yoshifumi Fujimoto, Yasumi Nakashima, Junji Sakata, Yasuyo Takeuchi, Makoto Motooka, Yasuhiko Tanaka, Nao Inoue, Hideki Saito, Yasuo Ono and 2 more

Abstract read
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In one paragraph

Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aya MiyazakiDepartment of Adult Congenital Heart Disease, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Naka-Ku, Hamamatsu, 430-8558, Japan. ayamiya@pc4.so-net.ne.jp.
Yoshifumi FujimotoDivision of Congenital Heart Disease, Department of Transitional Medicine, Shizuoka General Hospital, Shizuoka, Japan.
Yasumi NakashimaDepartment of Adult Congenital Heart Disease, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Naka-Ku, Hamamatsu, 430-8558, Japan.
Junji SakataDepartment of Cardiovascular Medicine, Shizuoka General Hospital, Shizuoka, Japan.
Yasuyo TakeuchiDepartment of Cardiovascular Medicine, Shizuoka General Hospital, Shizuoka, Japan.
Makoto MotookaDepartment of Cardiovascular Medicine, Shizuoka General Hospital, Shizuoka, Japan.
Yasuhiko TanakaDivision of Congenital Heart Disease, Department of Transitional Medicine, Shizuoka General Hospital, Shizuoka, Japan.
Nao InoueDepartment of Adult Congenital Heart Disease, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Naka-Ku, Hamamatsu, 430-8558, Japan.
Hideki SaitoDepartment of Adult Congenital Heart Disease, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Naka-Ku, Hamamatsu, 430-8558, Japan.
Yasuo OnoDivision of Congenital Heart Disease, Department of Transitional Medicine, Shizuoka General Hospital, Shizuoka, Japan.
Hiroki SakamotoDepartment of Cardiovascular Medicine, Shizuoka General Hospital, Shizuoka, Japan.
Hisashi SugiyamaDepartment of Adult Congenital Heart Disease, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Naka-Ku, Hamamatsu, 430-8558, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The standard value of heart rate (HR) and the effect of HR on Fontan circulation remain unclear. HRs and hemodynamic parameters were evaluated in 59 adults with Fontan circulation without pacemaker (PM) and then compared with those of 15 patients with PM. The minimum HR in Holter monitoring, HR in resting electrogram, resting HR in cardiopulmonary exercise (CPX), maximum HR in Holter, and peak HR in CPX were observed during sleep, supine, sitting, maximum daily activity, and exercise, respectively. HRs in 15 patients with excellent status of Fontan circulation were 50 ± 6, 75 ± 15, 81 ± 7, 86 ± 11, 141 ± 19, and 165 ± 17 bpm in sleep, in supine, Holter mean, in sitting, during maximum daily activity, and during exercise, respectively. Among 59 patients, the higher HR during exercise and higher ΔHR between exercise and sleep were associated with favorable values of hemodynamics. The PM group had higher HR during sleep and lower HR during the activities above the sitting position, compared with the non-PM group. The standard values for adults with Fontan circulation would be approximately 50, 75, 80, 85, 140, and 165 bpm during sleep, in the supine position, Holter mean, in the sitting position, during maximum daily activity, and during exercise, respectively. The higher HR during activities may facilitate the maintenance of good Fontan circulation. After PM implantation for Fontan circulation, the setting of increased HR during activities as well as the efforts to maintain narrow QRS duration and atrioventricular synchrony should be kept in mind.

Indexed as

Fontan ProcedureHeart Defects, CongenitalHeart RateHemodynamicsAdolescentAdultElectrocardiography, AmbulatoryExerciseExercise TestFemaleHumansMaleSleepYoung AdultCardiopulmonary exerciseFontanHeart rateHolter monitoringPacemakerSinus node dysfunction

Identifiers

PMID40968188

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.