Evidence map›Paper›PMID 40968523›Full record

ArticleThe clinical respiratory journal2025

Prevalence, Distribution, and Risk Factors of Mycobacterium Other Than Tuberculosis Among Tuberculosis Presumptive Patients in Karonga District in Malawi.

S Chitsulo, L Gogoda, H Nyirenda, S Chirwa, T Mwenyenkulu, H Kanyerere, J Mpunga, K Mbendera, B Mbakaya, S Mwale and 3 more

Abstract read
In one paragraph

Article in The clinical respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

S ChitsuloMalawi Ministry of Health, National TB and Leprosy Elimination Program, Lilongwe, Central Region, Malawi.ORCID https://orcid.org/0000-0001-5960-8326
L GogodaMalawi Ministry of Health, National TB and Leprosy Elimination Program, Lilongwe, Central Region, Malawi.
H NyirendaMalawi Ministry of Health, National TB and Leprosy Elimination Program, Lilongwe, Central Region, Malawi.
S ChirwaMalawi Ministry of Health, National TB and Leprosy Elimination Program, Lilongwe, Central Region, Malawi.
T MwenyenkuluMalawi Ministry of Health, National TB and Leprosy Elimination Program, Lilongwe, Central Region, Malawi.
H KanyerereMalawi Ministry of Health, National TB and Leprosy Elimination Program, Lilongwe, Central Region, Malawi.
J MpungaMalawi Ministry of Health, National TB and Leprosy Elimination Program, Lilongwe, Central Region, Malawi.
K MbenderaMalawi Ministry of Health, National TB and Leprosy Elimination Program, Lilongwe, Central Region, Malawi.
B MbakayaFaculty of Science Technology and Innovation, Mzuzu University, Mzuzu, Northen Region, Malawi.ORCID https://orcid.org/0000-0002-4705-9064
S MwaleFaculty of Science Technology and Innovation, Mzuzu University, Mzuzu, Northen Region, Malawi.
B NyambaloMalawi Ministry of Health, National TB and Leprosy Elimination Program, Lilongwe, Central Region, Malawi.
F SinyizaMzuzu Central Hospital, Mzuzu, Northern Region, Malawi.
M ChisaleFaculty of Science Technology and Innovation, Mzuzu University, Mzuzu, Northen Region, Malawi.

Funding

Global Fund and World BankGlobal Fund to Fight AIDS, Tuberculosis and MalariaSouthern Africa TB and Health Systems Support Project (SATHSSP)World bank-SATBHSSP
6 · The paper itself

Abstract

introductionBesides tuberculosis (TB), there are also other nontuberculous mycobacteria (NTM) that present with similar clinical signs and symptoms as TB. If not promptly found and treated, these organisms may affect the programming of the TB control and elimination campaign. The study sought to establish the prevalence, distribution, and factors contributing to MOTT infections among presumptive TB patients in the Karonga district.

methodsA descriptive cross-sectional study research design was employed. A total of 196 participants were included in the study using a census approach. Data were collected by administering a questionnaire to the health care worker, and a sputum specimen was collected from the participants; this specimen was used to examine the presence of mycobacterium using the microscope. Regardless of the results at the district-level laboratory, all the specimens were then sent to the Mzuzu region TB reference laboratory to isolate Mycobacterium tuberculosis and Mycobacterium Other Than Tuberculosis.

resultsOf the 196 samples collected, 14 (7.1%) were positive at the district level. When sent for culture, 195 (99.5%) had culture results, and 23 (12%) had growth in culture. Out of the 23 (100%) culture-positive results, 12 (52%) were MOTT-positive, while 11 (48%) were MTB complex. There were more men, seven (58%) with MOTT-positive than women, five (42%), and more in the age group of 15-39 years old, with six (50%) and less in more than 60 years old two (16.7%).

conclusionThe results show the presence of MOTT infections among presumptive TB patients who submitted samples to the study. The distribution by sex shows that more men had MOTT infections than women. However, all the risk factors listed for the study were not significant for MOTT infections. The recommendation is to improve the testing techniques to identify these microorganisms, which are neglected but very difficult to assess, especially when no clear population is at risk of getting these infections compared with TB.

Indexed as

Mycobacterium Infections, NontuberculousNontuberculous MycobacteriaTuberculosisAdolescentAdultAgedCross-Sectional StudiesFemaleHumansMalawiMaleMiddle AgedMycobacterium tuberculosisPrevalenceRisk FactorsSputumMOTTmycobacteriumpresencepresumptive

Identifiers

PMID40968523
PMCPMC12446564

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.