Evidence map›Paper›PMID 40968739›Full record

ArticleClinical and experimental dental research2025

Investigation of the Combined Impact of Zinc Oxide Nanoparticles and Bacterial Cellulose Nanocrystals on the Bond Strength to Dentin and Fracture Resistance of Resin-Modified Glass Ionomer Cement in Primary Molars.

Ali Nozari, Fatemeh Parvizi, Zahra Jowkar, Farnaz Haji Abbas Oghli, Hosein Askari, Seyed Ahmadreza Hamidi

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Article in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ali NozariDepartment of Pediatric Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Fatemeh ParviziDepartment of Pediatric Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Zahra JowkarOral and Dental Disease Research Center, Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0003-4447-3670
Farnaz Haji Abbas OghliDepartment of Pediatric Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0001-6279-3008
Hosein AskariDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyed Ahmadreza HamidiDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

This research (Number: 30432) was financially supported by Shiraz University of Medical Sciences, Shiraz, Iran.
6 · The paper itself

Abstract

objectivesThis study aimed to evaluate the microshear bond strength (µSBS) of resin-modified glass ionomer cement (RMGIC) to primary dentin and the fracture resistance of primary molars restored with RMGIC, with and without the incorporation of mesoporous zinc oxide nanoparticles (ZnO NPs) and bacterial cellulose nanocrystals (BCNCs). MATERIALS AND

methodsA total of 100 extracted primary mandibular second molars were divided into two tests: the µSBS test (40 teeth) and the fracture resistance test (60 teeth). The µSBS test included four groups: (1) RMGIC (control), (2) RMGIC + 5 wt.% mesoporous ZnO NPs, (3) RMGIC + 1 wt.% BCNCs, and (4) RMGIC + 5 wt.% mesoporous ZnO NPs and 1 wt.% BCNCs. The fracture resistance test included these groups along with an intact teeth group (positive control) and a prepared but unrestored teeth group (negative control). A universal testing machine was used for all mechanical tests.

resultsThe RMGIC + 1 wt.% BCNCs group exhibited the highest µSBS (6.35 ± 1.98 MPa), significantly surpassing the control and other experimental groups (p < 0.001). For fracture resistance, the negative control had the lowest value (422.70 ± 44.50 N, p < 0.05), while the positive control had the highest, significantly outperforming all groups except RMGIC + 1 wt.% BCNCs (p > 0.05). The RMGIC + 1 wt.% BCNCs group (1280.40 ± 340.87 N) demonstrated significantly greater fracture resistance than both RMGIC and RMGIC + 5 wt.% mesoporous ZnO (p < 0.05).

conclusionsIncorporating 1 wt.% BCNCs into RMGIC significantly enhanced both microshear bond strength and fracture resistance, leading to a higher proportion of restorable fractures. The positive correlation between bond strength and fracture resistance suggests that BCNCs-modified RMGIC is a promising restorative material for improving durability in primary molars.

Indexed as

CelluloseDental BondingDentinGlass Ionomer CementsMolarNanoparticlesTooth, DeciduousTooth FracturesZinc OxideDental Stress AnalysisHumansIn Vitro TechniquesMaterials TestingCelluloseGlass Ionomer CementsZinc Oxidebacterial cellulose nanocrystalsfracture resistancemesoporous zinc oxide nanoparticlesmicroshear bond strength

Identifiers

PMID40968739
PMCPMC12446879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.