Evidence map›Paper›PMID 40968786›Full record

Trial reportPsycho-oncology2025

Randomized Controlled Trial of Group-Blended and Individual-Unguided Online Mindfulness-Based Cognitive Therapy to Reduce Psychological Distress in People With Cancer.

Nasim Badaghi, Linda Kwakkenbos, Judith Prins, Rogier Donders, Saskia Kelders, Anne Speckens

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05336916 (), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05336916 naunknown statusnot on this map

(Cost)Effectiveness of Blended and UnguideD DeliverY of Mindfulness-based Cognitive Therapy Versus Care as Usual for Cancer Patients: BUDDY Project

TypeinterventionalSponsorRadboud University Medical CenterRan2021 to 2023Enrolled254ConditionsCancerArmsBuddy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nasim BadaghiDepartment of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands.
Linda KwakkenbosDepartment of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands.
Judith PrinsDepartment of Medical Psychology, Radboud University Medical Center, Nijmegen, the Netherlands.
Rogier DondersDepartment of IQ Health, Radboud University Medical Center, Nijmegen, the Netherlands.
Saskia KeldersDepartment of Psychology, Health, and Technology, University of Twente, Enschede, the Netherlands.
Anne SpeckensDepartment of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands.

Funding

KWF Kankerbestrijding
6 · The paper itself

Abstract

objectiveOnline mindfulness-based cognitive therapy (eMBCT) can reduce psychological distress in people with cancer, but adherence and scalability could be improved. Through co-creation, we developed two eMBCT formats: group-blended and individual-unguided. This trial compared the effects of the two eMBCT to care as usual (CAU) on psychological distress and other mental health outcomes in people with cancer.

methodsIn this parallel, three-armed randomized controlled trial, people with cancer were randomly allocated to group-blended eMBCT, individual-unguided eMBCT, or CAU. Participants completed baseline, mid-treatment, post-treatment, and 3 months follow-up assessments. The primary outcome analyzed in the intention-to-treat (ITT) population was psychological distress (Hospital Anxiety and Depression Scale) at post-treatment.

resultsIn total, 186 participants were randomized to group-blended eMBCT (N = 57), individual-unguided eMBCT (N = 75), or CAU (N = 54). Most participants were female (81%) with breast cancer (49%), and treated with curative intent (76%). In ITT analyses, group-blended eMBCT participants reported significantly lower levels of psychological distress at post-treatment (Cohen's d = 0.38) and follow-up (Cohen's d = 0.64) than those receiving CAU, while individual-unguided eMBCT participants only had significantly less psychological distress at follow-up (Cohen's d = 0.48). Additionally, participants in group-blended eMBCT had less rumination and greater mindfulness, decentering, and self-compassion than those in CAU at follow-up. Participants in individual-unguided eMBCT had greater decentering than those in CAU at post-treatment and follow-up, and less rumination and greater mindfulness skills than CAU at follow-up.

conclusionsCompared to CAU, both eMBCT conditions were effective in reducing psychological distress and could be an accessible, and potentially low-cost intervention to reduce distress in people with cancer.

trial registrationDutch Registry CCMO, NL73117.091.20; clinicaltrials.gov, NCT05336916.

Indexed as

Cognitive Behavioral TherapyDepressionMindfulnessNeoplasmsPsychological DistressPsychotherapy, GroupStress, PsychologicalAdultAgedAnxietyFemaleHumansInternet-Based InterventionMaleMiddle AgedTreatment Outcomecancermindfulnessoncologypsycho‐oncologyrandomized controlled trial

Identifiers

PMID40968786
PMCPMC12447259

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.