ArticleSensors (Basel, Switzerland)2025
Design and Structure of a Non-Coaxial Multi-Focal Composite Fresnel Acoustic Lens for Synergistic Ultrasound Stimulation of Multiple Brain Regions.
Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- High-Frequency Ultrasound Focusing Using Low-Cost PMMA and PDMS Acoustic Lenses.Micromachines · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
Transcranial focused ultrasound (TcFUS) neuromodulation is hindered by skull-induced acoustic limitations. To enable synergistic multi-region brain stimulation, we designed non-coaxial multi-focal composite Fresnel acoustic lenses, including an overlapping Fresnel lens (OFL) and an alternating-segmented Fresnel lens (ASFL). These lenses convert planar ultrasound into multiple foci. Based on Fresnel theory, acoustic fields were analyzed via simulations and experiments, validating the generation of four non-coaxial foci (10/30 mm focal lengths) from a 1 MHz planar wave using both OFL and ASFL. The influence of lens parameters on focal pressure distribution was investigated, and morphology was quantified using a linear least-squares method. Significant differences in focal morphology and intensity between OFL and ASFL provide crucial guidance for optimizing multi-target TcFUS strategies.
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Registered trials
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