Evidence map›Paper›PMID 40968921›Full record

ArticleSensors (Basel, Switzerland)2025

Effects of Passive Hip Flexion and Extension Assistance in Patients with Peripheral Artery Disease and Healthy Individuals.

Hiva Razavi, Sara A Myers, Iraklis I Pipinos, Philippe Malcolm

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hiva RazaviDepartment of Biomechanics, University of Nebraska at Omaha, Omaha, NE 68182, USA.ORCID 0000-0003-0554-0121
Sara A MyersDepartment of Biomechanics, University of Nebraska at Omaha, Omaha, NE 68182, USA.ORCID 0000-0002-2934-2624
Iraklis I PipinosDepartment of Surgery and Research Service, Nebraska-Western Iowa Veterans Affairs Medical Center, Omaha, NE 68105, USA.ORCID 0000-0001-6873-6346
Philippe MalcolmDepartment of Biomechanics, University of Nebraska at Omaha, Omaha, NE 68182, USA.ORCID 0000-0003-4110-4167

Funding

Visual control of locomotion in people with Parkinsons diseaseP20GM109090 · NIGMS · UNIVERSITY OF NEBRASKA OMAHA · PI MANGALAM, MADHUR · 2014 to 2023
$20.5M
Tissue Analysis Core (TAC)P20GM152301 · NIGMS · UNIVERSITY OF NEBRASKA OMAHA · PI Alexey Kamenskiy · 2024 to 2026
$8.8M
MitoQ treatment of claudication: myofiber and micro-vessel pathologyR01AG077803 · NIA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Iraklis Ilias Pipinos · 2022 to 2026
$3.0M
NIA NIH HHS R01 AG077803NIGMS NIH HHS P20 GM109090NIGMS NIH HHS P20 GM152301NIH HHS P20GM109090NIH HHS P20GM152301NIH HHS R01AG077803U.S. National Science Foundation 2203143
6 · The paper itself

Abstract

(1) Background: Peripheral artery disease (PAD) and related conditions significantly impair walking ability. Previous studies demonstrated that passive lightweight exosuits can improve walking biomechanics. However, most of these devices focus on assisting hip flexion. The aim of this study was to investigate the effects of flexion and extension assistance on joint kinetics and muscle activation. We hypothesized that there would be an optimal combination of flexion and extension assistance for measured parameters. (2) Methods: Four patients with PAD and six healthy individuals walked on a treadmill while wearing a passive exosuit with adjustable hip flexion and extension assistance. Lower limbs' power, moment, and muscle activation were recorded. (3) Results: We found that passive hip assistance effectively reduced hip kinetics in both healthy and PAD participants. We also found different effects between the groups, with the PAD group utilizing the exosuit to reduce plantarflexion kinetics and gastrocnemius activity. (4) Conclusions: These findings suggest that patients with PAD can leverage the exosuit to ameliorate impairment-specific deficits. Future research should explore more real-world applicability of passive exosuits.

Indexed as

HipHip JointPeripheral Arterial DiseaseAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedMuscle, SkeletalRange of Motion, ArticularWalkingarterial occlusive diseaseelastic exosuitelectromyographyexoskeletongait rehabilitationintermittent claudicationwalking assistancewearable assistive devicewearable robotics

Identifiers

PMID40968921
PMCPMC12157799

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.