Evidence map›Paper›PMID 40969323›Full record

ArticleF1000Research2025

Modeling and Analysis of SIRR Model (Ebola Transmission Dynamics Model) with Delay Differential Equation.

Akinleye Emmanuel Lasekan, Joshua Oluwasegun Agbomola, Kabir Oluwatobi Idowu, Babatunde Ademola Kannike, Esther Oluwatoyin Mulero, Temitope Senami Gandonu, Solari Myrjuari Elee

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Article in F1000Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Akinleye Emmanuel LasekanDepartment of Mathematics, Lagos State University, Ojo, Lagos, Nigeria.ORCID https://orcid.org/0009-0001-0580-9584
Joshua Oluwasegun AgbomolaDepartment of Mathematics, Tulane University, New Orleans, Louisiana, USA.
Kabir Oluwatobi IdowuDepartment of Mathematics, Purdue University, West Lafayette, Indiana, USA.ORCID https://orcid.org/0000-0003-1345-4995
Babatunde Ademola KannikeDepartment of Mathematics, Lagos State University, Ojo, Lagos, Nigeria.
Esther Oluwatoyin MuleroDepartment of Mathematics, Lagos State University, Ojo, Lagos, Nigeria.ORCID https://orcid.org/0009-0009-0825-2177
Temitope Senami GandonuDepartment of Mathematics, Tulane University, New Orleans, Louisiana, USA.
Solari Myrjuari EleeDepartment of Mathematics, University of Delaware, Newark, Delaware, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ebola virus disease (EVD) is a severe and often fatal illness with high transmission potential and recurring outbreaks. Traditional compartmental models often neglect biologically important delays, such as the latent period before an infected individual becomes infectious, limiting their ability to capture real-world epidemic patterns. Including such delays can provide a more accurate understanding of outbreak persistence and control strategies. Methods: In this study, we develop and analyze a novel deterministic SIRR model that captures the complex transmission dynamics of Ebola by explicitly combining nonlinear incidence rates with a delay differential equation framework. Unlike traditional models, this approach integrates a biologically motivated delay to represent the latent period before infectiousness, providing a more realistic depiction of disease spread. The basic reproduction number (R Results: The main novelty of this work lies in its detailed investigation of how delays influence outbreak persistence and can trigger oscillatory epidemics, patterns often observed in practice but rarely captured by classic models. For R Conclusions: Accounting for delayed recovery dynamics is crucial for accurately predicting outbreak patterns and designing effective interventions. This delay-based, nonlinear-incidence model offers a robust analytical and computational framework for guiding public health strategies, with direct implications for reducing transmission, shortening outbreak duration, and preventing epidemic resurgence.

Indexed as

Epidemiological ModelsHemorrhagic Fever, EbolaModels, BiologicalBasic Reproduction NumberComputer SimulationDisease OutbreaksEbolavirusEpidemicsHumansBifurcation Analysiscenter manifold theorydelay differential equationEquilibrium point \sep stabilitySIRR model

Identifiers

PMID40969323
PMCPMC12441668

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.