ReviewFrontiers in psychiatry2025
Cannabis use in adolescence and young adulthood and its effects on brain structure and function: a scoping review.
Review in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Adolescent Cannabis Use After Cannabis Legalization and the COVID-19 Pandemic.JAMA network open · 2026Article
- Cannabis use in adolescence and young adulthood and its effects on brain structure and function: a scoping review.Frontiers in psychiatry · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Adolescence and young adulthood are simultaneously periods of significant brain development and the ages in which people often initiate cannabis use. This has led to significant interest in researching the effects that cannabis use in this period might have on the brains of users. This scoping review aims to summarize existing neuroimaging research on the effect of cannabis use in adolescence and/or young adulthood (ages 14-25) on brain structure, function, and metabolite concentrations. Methods: Following scoping review methodology, databases containing neuroimaging studies assessing the effects of cannabis use between the ages of 14 and 25 on brain structure, function, and metabolite concentrations were searched. Results: Our search yielded 3901 sources, of which 99 met inclusion criteria. The majority of included papers (84/99) found differences in the brain structure, function, and/or metabolite concentrations of adolescent/young adult cannabis users compared to non-using controls. Fewer studies explicitly assessed sex/gender differences, with 5 finding that sex/gender influenced the effect of cannabis use on the brain. Conclusion: Based on the findings of this review, there is considerable evidence to suggest that cannabis use in adolescence/young adulthood causes changes in the brains of users, however, the low quality of relevant research and scarcity of long term follow up studies, in addition to the heterogeneity of the existing research suggests that more work needs to be done to understand this relationship.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.