Evidence map›Paper›PMID 40970261›Full record

ArticleClinical case reports2025

Xerophthalmia and Nyctalopia as Presenting Signs of Vitamin A Deficiency in a Patient With Rapid Intentional Weight Loss: A Case Report and Literature Review.

Nasser Shoeibi, Sahel Khazaei, Mehrdad Motamed Shariati

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Significance of Vitamins A and E in Cancer Progression and Prevention.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nasser ShoeibiEye Research Center Mashhad University of Medical Sciences Mashhad Iran.
Sahel KhazaeiEye Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-6609-3831
Mehrdad Motamed ShariatiEye Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-8680-5560

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To present a patient with xerophthalmia and night blindness secondary to vitamin A deficiency following rapid weight loss. A 34-year-old man presented with decreased night vision, foreign body sensation, and eye dryness. He reported a rapid intentional weight loss of approximately 34 kg over the past 4 months through a restricted diet. Slit lamp examination revealed severe dry eye and a foamy appearance of the bulbar conjunctiva in both eyes. Retinal inner atrophy was evident on macular optical coherence tomography imaging. This case highlights critical considerations for clinical practice, particularly in managing patients experiencing rapid weight loss. It emphasizes the importance of thorough nutritional assessments in individuals undergoing significant weight changes, whether due to intentional dieting, bariatric surgery, or illness. Early identification of at-risk individuals facilitates timely intervention, including dietary counseling, supplementation, and, if necessary, referral to specialists in nutrition or gastroenterology.

Indexed as

conjunctival xerosisnyctalopiavitamin A deficiencyweight loss

Identifiers

PMID40970261
PMCPMC12441006

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.