Evidence map›Paper›PMID 40974309›Full record

ArticleJournal of the American Chemical Society2025

Conformational Plasticity of LptC Regulates Lipopolysaccharide Transport by the LptB

Aaron Klausnitzer, Jagdeep Kaur, Tobias Rath, Samuel Seidl, Johanna Becker-Baldus, Nina Morgner, Clemens Glaubitz

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aaron KlausnitzerInstitute for Biophysical Chemistry and Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Max von Laue Straße 9, 60438 Frankfurt am Main, Germany.
Jagdeep KaurInstitute for Biophysical Chemistry and Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Max von Laue Straße 9, 60438 Frankfurt am Main, Germany.
Tobias RathInstitute of Physical and Theoretical Chemistry, Goethe University Frankfurt, Max von Laue Straße 9, 60438 Frankfurt am Main, Germany.
Samuel SeidlInstitute for Biophysical Chemistry and Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Max von Laue Straße 9, 60438 Frankfurt am Main, Germany.
Johanna Becker-BaldusInstitute for Biophysical Chemistry and Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Max von Laue Straße 9, 60438 Frankfurt am Main, Germany.ORCID 0000-0003-1995-7323
Nina MorgnerInstitute of Physical and Theoretical Chemistry, Goethe University Frankfurt, Max von Laue Straße 9, 60438 Frankfurt am Main, Germany.ORCID 0000-0002-1872-490X
Clemens GlaubitzInstitute for Biophysical Chemistry and Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Max von Laue Straße 9, 60438 Frankfurt am Main, Germany.ORCID 0000-0002-3554-6586

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outer membrane of Gram-negative bacteria is coated with lipopolysaccharide (LPS). The Lpt system generates membrane asymmetry by transporting LPS from the inner to the outer membrane. Transport begins with the LptB

Indexed as

ATP-Binding Cassette TransportersEscherichia coli ProteinsLipopolysaccharidesBiological TransportEscherichia coliMembrane ProteinsModels, MolecularProtein ConformationATP-Binding Cassette TransportersEscherichia coli ProteinsLipopolysaccharidesLptC protein, E coliMembrane Proteins

Identifiers

PMID40974309
PMCPMC12498426

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.