Evidence map›Paper›PMID 40974439›Full record

ArticleWorld journal of urology2025

Outcomes of Percutaneous Nephrolithotomy in Kidney Transplant Recipients: Results from a Multicenter Study by the Spanish Urology Association's Renal Transplant Group.

A Sierra, H Alfambra, J M López, A Mercadé, L L Peri, R Espílez, M Álvarez-Maestro, R Martínez-Corral, D A Pérez-Fentes, B Etcheverry and 6 more

Abstract readMulticenter Study
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Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

A Sierra *Department of Urology, Hospital Clínic - University of Barcelona, Barcelona, Spain. asierradelrio@gmail.com.
H Alfambra *Department of Urology, Hospital Clínic - University of Barcelona, Barcelona, Spain.
J M LópezDepartment of Urology, Hospital Clínic - University of Barcelona, Barcelona, Spain.
A MercadéDepartment of Urology, Hospital Clínic - University of Barcelona, Barcelona, Spain.
L L PeriDepartment of Urology, Hospital Clínic - University of Barcelona, Barcelona, Spain.
R EspílezDepartment of Urology, Hospital Miquel Servet, Zaragoza, Spain.
M Álvarez-MaestroDepartment of Urology, Hospital Universitario La Paz, Madrid, Spain.
R Martínez-CorralDepartment of Urology, Complexo Hospitalario Santiago de Compostela, Santiago de Compostela, La Coruña, Spain.
D A Pérez-FentesDepartment of Urology, Complexo Hospitalario Santiago de Compostela, Santiago de Compostela, La Coruña, Spain.
B EtcheverryDepartment of Urology, Hospital de Bellvitge, Hospitalet de Llobregat, Spain.
S ColomDepartment of Urology, Hospital de Bellvitge, Hospitalet de Llobregat, Spain.
F ViguésDepartment of Urology, Hospital de Bellvitge, Hospitalet de Llobregat, Spain.
A AlcarazDepartment of Urology, Hospital Clínic - University of Barcelona, Barcelona, Spain.
M P LuqueDepartment of Urology, Hospital Clínic - University of Barcelona, Barcelona, Spain.
C TorrecillaDepartment of Urology, Hospital de Bellvitge, Hospitalet de Llobregat, Spain.
M MusqueraDepartment of Urology, Hospital Clínic - University of Barcelona, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStone disease amongst kidney transplant recipients (KTR) may not only lead to significant morbidity but also compromise graft function. In this context, percutaneous nephrolithotomy (PCNL) has emerged as a fundamental minimally invasive surgical technique for the treatment of kidney stones in KTR. The aim of this study is to evaluate the outcomes of PCNL in KTR in a nationwide series, encompassing operative results, stone-free rate (SFR), stone composition and renal graft function. MATERIALS &

methodsRetrospective data from five Spanish tertiary hospitals was analysed. All KTR that underwent PCNL between January 2005 and August 2024 were included in the study. Stone characteristics, postoperative complications, and surgical outcomes were evaluated.

resultsThe study included 39 KTR, median age 59 (32-82) years, predominantly male (71.8%). Most KTR received grafts from cadaveric donors (n = 35). Even though stone diagnosis was often incidental (64.1%), 74.3% of KTR experienced stone-related events before surgery, such as acute kidney failure (53.8%) and sepsis (15.4%). Diagnosis occurred after a median of 53 (0-264) months post-transplant. Preoperative nephrostomy insertion was common (59.0%), and 48.7% of KTR had positive urine cultures. Median stone size was 14 (5-50) mm with 53.8% of KTR having multiple stones. Median stone density was 720 (130-1770) HU. Overall complication rate after PCNL was 10.2%: 2 patients presented with urinary septic shock, 1 patient experienced puncture site bleeding requiring embolization and 1 haematuria accompanied by acute renal failure. Stone-free rate was 82.0% in the first procedure, with secondary treatments being successful when needed. The most frequent stone composition was calcium oxalate monohydrate (55.2%).

conclusionsIn our experience, PCNL is an effective and safe technique for addressing nephrolithiasis in KTR. SFR and complication rates may be comparable to those reported in PCNL performed in native kidneys. Furthermore, patients tend to benefit from surgical care in high-volume centres that possess dedicated expertise in both KT and endourology.

Indexed as

Kidney CalculiKidney TransplantationNephrolithotomy, PercutaneousAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesSpainTreatment OutcomeEndourologyKidney transplantPCNLPercutaneous neprolithotomyRenal graftRenal stones

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.