Evidence map›Paper›PMID 40974524›Full record

ArticleUpdates in surgery2025

Histopathologic regression in lymph nodes predicts occult metastasis in ypT0 colorectal cancers after neoadjuvant therapy: a retrospective cohort study.

Chaoyuan Xiao, Yu Shen, De He, Hai-Ning Chen

Abstract read
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In one paragraph

Article in Updates in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chaoyuan Xiao *Department of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Yu Shen *Department of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
De HeDepartment of Pathology, West China Hospital, Sichuan University, Chengdu, China.
Hai-Ning ChenDepartment of General Surgery, Colorectal Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China. hnchen@scu.edu.cn.ORCID http://orcid.org/0000-0003-0104-8498

Funding

National Natural Science Foundation of China 82073246National Natural Science Foundation of China 82373029
6 · The paper itself

Abstract

In locally advanced colorectal cancer (LACRC), neoadjuvant therapy (NT) followed by total mesorectal or complete mesocolic excision is standard. Although a pathological complete response at the primary site (ypT0) predicts excellent survival, this benefit is offset when residual nodal metastasis (ypT0N

Indexed as

Colorectal NeoplasmsLymphatic MetastasisLymph NodesNeoadjuvant TherapyAdultAgedCohort StudiesFemaleHumansMaleMiddle AgedNeoplasm StagingRetrospective StudiesColorectal cancerHistopathologic regressionLymph node metastasisNeoadjuvant therapyypT0N+

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.